Reiffel James A
Columbia University, New York, NY, USA.
Arrhythm Electrophysiol Rev. 2017 Dec;6(4):161-166. doi: 10.15420/aer.2017.33.1.
Thromboembolic stroke and systemic embolism are generally agreed to be the major morbidity/mortality concerns for patients with AF. However, the risk of thromboembolism is not the same for all AF patients. Both AF and comorbidities must interact synergistically to create the risk for thromboembolism. But, is the synergism dichotomous - AF present or absent, comorbid disorder present or absent - or does synergism have magnitude, depending on the number and severity of the associated disorders and the amount of time one is in AF? This review discusses the current risk-score contributors and options for assessing risk of thromboembolism in AF patients, and what their combined roles might be. Also covered is the consideration of left atrial appendage anatomy in this context.
血栓栓塞性中风和全身性栓塞通常被认为是房颤患者主要的发病/死亡风险因素。然而，并非所有房颤患者发生血栓栓塞的风险都相同。房颤和合并症必须协同作用才能产生血栓栓塞风险。但是，这种协同作用是二元的——存在房颤或不存在房颤、存在合并症或不存在合并症——还是协同作用具有程度差异，取决于相关疾病的数量和严重程度以及房颤持续的时间？本综述讨论了目前用于评估房颤患者血栓栓塞风险的风险评分因素和方法，以及它们可能的综合作用。本文还探讨了在这种情况下对左心耳解剖结构的考量。
