Refaat Marwan M, Ballout Jad, Mansour Moussa
Department of Internal Medicine, Cardiology Division,American University of Beirut, Lebanon.
Department of Biochemistry and Molecular Genetics,American University of Beirut, Lebanon.
Arrhythm Electrophysiol Rev. 2017 Dec;6(4):191-194. doi: 10.15420/2017.2017.15.1.
With improved surgical techniques and medical management for patients with congenital heart diseases, more patients are living longer and well into adulthood. This improved survival comes with a price of increased morbidity, mainly secondary to increased risk of tachyarrhythmias. One of the major arrhythmias commonly encountered in this subset of cardiac patients is AF. Similar to the general population, the risk of AF increases with advancing age, and is mainly secondary to the abnormal anatomy, abnormal pressure and volume parameters in the hearts of these patients and to the increased scarring and inflammation seen in the left atrium following multiple surgical procedures. Catheter ablation for AF has been shown to be a very effective treatment modality in patients with refractory AF. However, data and guidelines regarding catheter ablation in patients with congenital heart disease are not well established. This review will shed light on the procedural techniques, success rates and complications of AF catheter ablation in patients with different types of CHD, including atrial septal defects, tetralogy of Fallot, persistent left superior vena cava, heterotaxy syndrome and atrial isomerism, and Ebstein anomaly.
随着先天性心脏病患者手术技术和医疗管理的改进,越来越多的患者寿命延长,步入成年期。这种生存率的提高伴随着发病率增加的代价,主要是由于快速性心律失常风险增加。心房颤动(AF)是这类心脏病患者中常见的主要心律失常之一。与普通人群一样,AF的风险随着年龄增长而增加,主要是由于这些患者心脏的解剖结构异常、压力和容量参数异常,以及多次手术后左心房出现的瘢痕形成和炎症增加。对于难治性AF患者,导管消融已被证明是一种非常有效的治疗方式。然而,关于先天性心脏病患者导管消融的数据和指南尚未完善。本综述将阐明不同类型先天性心脏病(CHD)患者,包括房间隔缺损、法洛四联症、永存左上腔静脉、心脏异构综合征和心房异构症以及埃布斯坦畸形患者,进行AF导管消融的操作技术、成功率和并发症。