Liu I-Chen, Chen Pin-Chuan, Chau Lai-Kwan, Chang Guo-En
Opt Express. 2018 Jan 8;26(1):273-283. doi: 10.1364/OE.26.000273.
We propose and develop an intensity-detection-based refractive-index (RI) sensor for low-cost, rapid RI sensing. The sensor is composed of a polymer bent ridge waveguide (BRWG) structure on a low-cost glass substrate and is integrated with a microfluidic channel. Different-RI solutions flowing through the BRWG sensing region induce output optical power variations caused by optical bend losses, enabling simple and real-time RI detection. Additionally, the sensors are fabricated using rapid and cost-effective vacuum-less processes, attaining the low cost and high throughput required for mass production. A good RI solution of 5.31 10 × RIU is achieved from the RI experiments. This study demonstrates mass-producible and compact RI sensors for rapid and sensitive chemical analysis and biomedical sensing.
我们提出并开发了一种基于强度检测的折射率（RI）传感器，用于低成本、快速的RI传感。该传感器由低成本玻璃基板上的聚合物弯曲脊波导（BRWG）结构组成，并与微流体通道集成。流经BRWG传感区域的不同RI溶液会因光学弯曲损耗而导致输出光功率变化，从而实现简单实时的RI检测。此外，这些传感器采用快速且经济高效的无真空工艺制造，达到了大规模生产所需的低成本和高产量。通过RI实验实现了5.31×10⁻⁵RIU的良好RI溶液。本研究展示了可大规模生产且紧凑的RI传感器，用于快速灵敏的化学分析和生物医学传感。
