Bayne C G, Hunt W S, Johanson D C, Flynn E T, Weathersby P K
Undersea Biomed Res. 1985 Sep;12(3):327-32.
Decompression sickness in human beings exposed to high ambient pressure is thought to follow from gas bubble formation and growth in the body during return to low pressure. Detection of Doppler-shifted ultrasonic reflections in major blood vessels has been promoted as a noninvasive and sensitive indicator of the imminence of decompression sickness. We have conducted a double-blind, prospective clinical trial of Doppler ultrasonic bubble detection in simulated diving using 83 men, of whom 8 were stricken and treated for the clinical disease. Diagnosis based only on the Doppler signals had no correlation with clinical diagnosis. Bubble scores were only slightly higher in the stricken group. The Doppler technique does not appear to be of diagnostic value in the absence of other clinical information.
暴露于高环境压力下的人类发生减压病被认为是在返回低压过程中体内气泡形成和生长所致。检测大血管中多普勒频移超声反射已被推广为一种无创且灵敏的减压病即将发生的指标。我们对83名男性进行了一项关于模拟潜水时多普勒超声气泡检测的双盲前瞻性临床试验，其中8人患临床疾病并接受了治疗。仅基于多普勒信号的诊断与临床诊断无相关性。患病组的气泡评分仅略高。在没有其他临床信息的情况下，多普勒技术似乎没有诊断价值。
