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住院期间使用非典型抗精神病药物患者的代谢副作用

Metabolic Side Effects in Patients Using Atypical Antipsychotic Medications During Hospitalization.

作者信息

Dikeç Gül, Arabaci Leyla Baysan, Uzunoglu Gülçin Bölük, Mizrak Selin Demet

出版信息

J Psychosoc Nurs Ment Health Serv. 2018 Apr 1;56(4):28-37. doi: 10.3928/02793695-20180108-05. Epub 2018 Jan 12.

DOI:10.3928/02793695-20180108-05
PMID:29328360
Abstract

The current research evaluated metabolic side effects in inpatients (N = 271) using atypical antipsychotic medications in a psychiatric hospital in Turkey between June and December 2016. Data were collected via an information form created after reviewing the literature at the time of patients' hospitalization and discharge. According to the analysis, 73.8% of patients stated they experienced side effects from antipsychotic medications and 20.7% of patients experienced weight gain. A statistical difference was detected among body mass index, waist circumference, diastolic blood pressure, and heart rate during patient hospitalization and discharge. Patients using atypical anti-psychotic medications gained weight, had increased cardiovascular risk, and experienced adverse effects on their physical health during hospitalization. Mental health nurses should inform patients of medication effects and possible side effects, monitor side effects, and teach patients how to manage metabolic side effects. [Journal of Psychosocial Nursing and Mental Health Services, 56(4), 28-37.].

摘要

2016年6月至12月期间,在土耳其一家精神病医院,对271名使用非典型抗精神病药物的住院患者的代谢副作用进行了当前这项研究。数据通过在患者住院和出院时查阅文献后创建的信息表收集。根据分析,73.8%的患者表示他们经历了抗精神病药物的副作用,20.7%的患者体重增加。在患者住院和出院期间,体重指数、腰围、舒张压和心率之间检测到统计学差异。使用非典型抗精神病药物的患者在住院期间体重增加,心血管风险增加,身体健康受到不良影响。心理健康护士应告知患者药物作用和可能的副作用,监测副作用,并教导患者如何管理代谢副作用。[《心理社会护理与心理健康服务杂志》,56(4),28 - 37。]

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BMC Psychiatry. 2020 Aug 18;20(1):410. doi: 10.1186/s12888-020-02809-4.
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A Placebo-Controlled Study on the Treatment of Metabolic Syndrome of Qi Stagnation and Dampness Obstruction Related to Atypical Antipsychotics with Traditional Chinese Medicine (TCM).一项关于中药治疗与非典型抗精神病药物相关的气滞湿阻型代谢综合征的安慰剂对照研究。
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Cytokine Alterations in Schizophrenia: An Updated Review.
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Medicina (Kaunas). 2019 Jun 28;55(7):320. doi: 10.3390/medicina55070320.