MTA-SE NAP B Peripheral Nervous System Research Group, Department of Neurology, Semmelweis University, Balassa u. 6 Budapest, Hungary, 1083.
Department of Traumatology, Szt. István and László Hospital, Budapest, Hungary.
Muscle Nerve. 2018 Jun;57(6):994-999. doi: 10.1002/mus.26065. Epub 2018 Mar 14.
Hypervascularization of nerves has been shown to be a pathological sign in some peripheral nerve disorders, but has not been investigated in nerve trauma.
An observational cohort study was performed of the intraneural blood flow of 30 patients (34 nerves) with penetrating nerve injuries, before or after nerve reconstruction. All patients underwent electrophysiological assessment, and B-mode and color Doppler ultrasonography.
Intraneural hypervascularization proximal to the site of injury was found in all nerves, which was typically marked and had a longitudinal extension of several centimeters. In 6 nerves, some blood flow was also present within the injury site or immediately distal to the injury. No correlation was found between the degree of vascularization and age, size of the scar / neuroma, or degree of reinnervation.
Neovascularization of nerves proximal to injury sites appears to be an essential element of nerve regeneration after penetrating nerve injuries. Muscle Nerve 57: 994-999, 2018.
神经的高血管化已被证明是一些周围神经疾病的病理标志，但在神经创伤中尚未得到研究。
对 30 例（34 根神经）穿透性神经损伤患者的神经内血流进行了观察性队列研究，包括神经重建前后。所有患者均接受电生理评估、B 型和彩色多普勒超声检查。
在所有神经中均发现损伤部位近端的神经内高血管化，通常明显且具有数厘米长的纵向延伸。在 6 根神经中，损伤部位内或损伤部位近端也存在一些血流。血管化程度与年龄、疤痕/神经瘤的大小或再支配程度之间无相关性。
损伤部位近端神经的新生血管化似乎是穿透性神经损伤后神经再生的一个基本要素。肌肉神经 57:994-999,2018.
