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[外周动脉闭塞性疾病的纤维蛋白溶解疗法]

[Fibrinolytic therapy of peripheral arterial occlusive disease].

作者信息

Sailer S, Pilger E

出版信息

Wien Med Wochenschr. 1985 Aug 31;135(15-16):393-9.

PMID:2932859
Abstract

Occluded arterial segments can be recanalized by fibrinolytic drugs. In addition to systemic fibrinolysis another method of thrombolytic therapy has been established: Local thrombolytic therapy is carried out by infiltration of low dose of streptokinase into the thrombotic occlusion. According to the low dose streptokinase used and the short duration of therapy local thrombolysis is applicable in patients with high risks too. Therefore the range of indications to non-surgical recanalisations could be extended. The differential therapy depends on location, pathogenesis and clinical stage of the arterial occlusion.

摘要

闭塞的动脉段可用纤维蛋白溶解药物再通。除了全身纤维蛋白溶解外,还建立了另一种溶栓治疗方法:通过向血栓性闭塞处注入低剂量链激酶进行局部溶栓治疗。根据所用的低剂量链激酶和较短的治疗持续时间,局部溶栓也适用于高危患者。因此,非手术再通的适应证范围可以扩大。差异治疗取决于动脉闭塞的部位、发病机制和临床阶段。

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