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[急性动脉血栓形成的局部溶栓治疗]

[Local lysis therapy in acute arterial thrombosis].

作者信息

Roth F J, Rieser R, Scheffler A

机构信息

Aggertalklinik, Engelskirchen.

出版信息

Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir. 1990:427-34.

PMID:1983584
Abstract

Acute thrombotic arterial occlusion is a complication of chronic vascular arterial disease. The arteriogram usually reveals a sudden occlusion and the collateral vessels. Treatment with low-dose fibrinolytic therapy is widely accepted. A combination of low-dose fibrinolysis, aspiration embolectomy and angioplasty yields the best primary success rate. In cases of sudden popliteal occlusion and dilating arteriopathy ultrasound sonography should be used to exclude the presence aneurysm which is a contraindication for fibrinolysis. There is a high risk of peripheral embolisation, in the presence of an aneurysm and this may cause severe deterioration of the arterial blood supply.

摘要

急性血栓性动脉闭塞是慢性血管动脉疾病的一种并发症。动脉造影通常显示突然闭塞及侧支血管。低剂量纤维蛋白溶解疗法已被广泛接受。低剂量纤维蛋白溶解、抽吸性栓子切除术和血管成形术联合应用可获得最佳的初始成功率。对于突然发生的腘动脉闭塞和扩张性动脉病病例,应使用超声检查以排除存在动脉瘤,因为动脉瘤是纤维蛋白溶解的禁忌症。存在动脉瘤时,发生外周栓塞的风险很高,这可能导致动脉血供严重恶化。

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