Ražnatović-Đurović Milena, Janković Janko, Janković Slavenka
Vojnosanit Pregl. 2016 Nov;73(11):1016-21. doi: 10.2298/VSP150114138R.
BACKGROUND/AIM: Increasing epidemiological studies suggest the association between psoriasis and metabolic syndrome. The aim of this study was to assess the association of metabolic syndrome and its components with psoriasis in a sample of patients from Montenegro, and to predict the factors that determine the metabolic syndrome.
A case-control study was conducted at the Clinic of Dermatology and Venereology, Clinical Center of Montenegro, Podgorica, Montenegro, between January and December 2012. The study group included 101 patients with psoriasis (cases) and 126 patients with the diagnosis of dermatological disease other than psoriasis (controls) consecutively admitted to the same clinic.
Metabolic syndrome was more prevalent in the psoriasis patients than in the controls (48.5% vs 20.6%; OR = 2.99). In addition, the psoriasis patients were significantly more likely to be smokers (OR = 2.16) and were less physically active (OR = 0.58).
The results of this study demonstrate a strong association between psoriasis and metabolic syndrome independent of psoriasis severity. Patients with psoriasis should be routinely screened for metabolic syndrome and its components. [Projekat Ministarstva nauke Republike Srbije, br. 175025: Clinical-epidemiological research of diseases of public health importance in Serbia].
背景/目的:越来越多的流行病学研究表明银屑病与代谢综合征之间存在关联。本研究的目的是评估黑山患者样本中代谢综合征及其组成成分与银屑病之间的关联,并预测决定代谢综合征的因素。
2012年1月至12月期间,在黑山波德戈里察的黑山临床中心皮肤病与性病诊所进行了一项病例对照研究。研究组包括101例银屑病患者(病例组)和126例诊断为除银屑病外其他皮肤病的患者(对照组),这些患者均连续入住同一诊所。
银屑病患者中代谢综合征的患病率高于对照组(48.5%对20.6%;OR=2.99)。此外,银屑病患者吸烟的可能性显著更高(OR=2.16),身体活动较少(OR=0.58)。
本研究结果表明银屑病与代谢综合征之间存在密切关联,且与银屑病严重程度无关。银屑病患者应常规筛查代谢综合征及其组成成分。[塞尔维亚共和国科学部项目,编号175025:塞尔维亚具有公共卫生重要性疾病的临床流行病学研究]