Durham Veterans Affairs Medical Center, United States; VISN 6, Mental Illness Research, Education and Clinical Center (MIRECC), Durham, NC, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Durham Veterans Affairs Medical Center, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Psychiatry Res. 2018 Mar;261:274-280. doi: 10.1016/j.psychres.2017.12.080. Epub 2018 Jan 3.
This study employed secondary analyses of existing ecological momentary assessment (EMA) data to characterize hostile and irritable affect in the day-to-day experience of 52 smokers with, and 65 smokers without, posttraumatic stress disorder (PTSD). EMA monitoring occurred over a mean of 8.2 days, and participants responded to an average of 2.8 random prompts/day. Analyses included Wilcoxon rank sum tests of group differences, and path analyses of cross-lagged multilevel models. Participants with PTSD endorsed a significantly higher proportion of total EMA entries indicating hostile affect and irritable affect than did individuals without PTSD. Cross-lagged analyses indicated that over a period of hours, PTSD symptoms significantly predicted subsequent hostile and irritable affect, but hostile and irritable affect did not predict subsequent PTSD symptoms. Findings suggest that day-to-day exposure to PTSD-related trauma cues may contribute to chronically elevated levels of anger-related affect. Such heightened affective arousal may, in turn, underlie an increased risk for verbal or physical aggression, as well as other health and quality-of-life related impairments associated with PTSD. Clinical implications include conceptualizing anger treatment in the broader context of trauma history and symptoms, and specifically targeting physiological arousal and maladaptive hostile cognitions triggered by trauma reminders in patients with PTSD.
本研究利用现有的生态瞬时评估(EMA)数据进行二次分析,以描述 52 名患有创伤后应激障碍(PTSD)的吸烟者和 65 名没有 PTSD 的吸烟者在日常生活中的敌对和易怒情绪。EMA 监测平均持续 8.2 天,参与者平均每天回复 2.8 个随机提示。分析包括Wilcoxon 秩和检验组间差异,以及交叉滞后多层次模型的路径分析。患有 PTSD 的参与者表示敌对情绪和易怒情绪的 EMA 条目比例明显高于没有 PTSD 的参与者。交叉滞后分析表明,在数小时的时间内,PTSD 症状显著预测随后的敌对和易怒情绪,但敌对和易怒情绪并未预测随后的 PTSD 症状。研究结果表明,日常接触与 PTSD 相关的创伤线索可能导致与愤怒相关的情绪持续升高。这种情绪唤醒可能反过来增加言语或身体攻击的风险,以及与 PTSD 相关的其他健康和生活质量相关的损害。临床意义包括将愤怒治疗纳入创伤史和症状的更广泛背景,以及针对 PTSD 患者的创伤提醒引发的生理唤醒和适应不良的敌对认知进行具体治疗。