Giannopoulos Andreas A, Gaemperli Oliver
Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Zurich, Switzerland.
Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich, Zurich, Switzerland.
Rev Esp Cardiol (Engl Ed). 2018 May;71(5):382-390. doi: 10.1016/j.rec.2017.11.023. Epub 2018 Jan 10.
Hybrid imaging for ischemic heart disease refers to the fusion of information from a single or usually from multiple cardiovascular imaging modalities enabling synergistic assessment of the presence, the extent, and the severity of coronary atherosclerotic disease along with the hemodynamic significance of lesions and/or with evaluation of the myocardial function. A combination of coronary computed tomography angiography with myocardial perfusion imaging, such as single-photon emission computed tomography and positron emission tomography, has been adopted in several centers and implemented in international coronary artery disease management guidelines. Interest has increased in novel hybrid methods including coronary computed tomography angiography-derived fractional flow reserve and computed tomography perfusion and these techniques hold promise for the imminent diagnostic and management approaches of patients with coronary artery disease. In this review, we discuss the currently available hybrid noninvasive imaging modalities used in clinical practice, research approaches, and exciting potential future technological developments.
缺血性心脏病的混合成像指的是来自单一或通常来自多种心血管成像模式的信息融合，能够协同评估冠状动脉粥样硬化疾病的存在、范围和严重程度，以及病变的血流动力学意义和/或评估心肌功能。冠状动脉计算机断层扫描血管造影与心肌灌注成像（如单光子发射计算机断层扫描和正电子发射断层扫描）的联合应用已在多个中心采用，并纳入国际冠状动脉疾病管理指南。对包括冠状动脉计算机断层扫描血管造影衍生的血流储备分数和计算机断层扫描灌注在内的新型混合方法的兴趣日益增加，这些技术有望用于冠状动脉疾病患者的即时诊断和管理方法。在本综述中，我们讨论了目前临床实践中使用的混合无创成像模式、研究方法以及令人兴奋的未来潜在技术发展。
