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[西班牙胃肠病学家对牛奶蛋白过敏管理的态度]

[Attitudes towards cow's milk protein allergy management by spanish gastroenterologist].

作者信息

Pascual Pérez Alicia Isabel, Méndez Sánchez Alejandra, Segarra Cantón Óscar, Espin Jaime Beatriz, Jiménez Treviño Santiago, Bousoño García Carlos, Díaz Martín Juan José

机构信息

Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, Oviedo, España.

Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, Oviedo, España.

出版信息

An Pediatr (Engl Ed). 2018 Oct;89(4):222-229. doi: 10.1016/j.anpedi.2017.10.015. Epub 2018 Jan 10.

Abstract

INTRODUCTION

Food allergy is an increasing health problem in the developed world. Cow's milk protein is the main cause of food allergy in infants. Without an appropriate diagnostic workup, there is a high risk of both over- and underdiagnosis and therefore, over and undertreatment. The objective of our study was to analyze the variability in cow's milk protein allergy (CMPA) management by pediatric gastroenterologists in Spain.

METHODS

A fifty item questionnaire, including open and closed items in a Likert's scale from 0 to 5, was drafted and distributed through the Spanish Society for Pediatric Gastroenterology, Hepatology and Nutrition (SEGHNP) e-mail list.

RESULTS

Seventy-three questionnaires were received back out of 321. Only 3 of the items achieved concordance greater than 90%. Thirty-three percent considered oral challenge to be necessary for the diagnosis of CMPA under any circumstance. Twenty-five percent considered that symptom improvement after cow's milk removal was enough for the diagnosis. Oral challenge was performed at home by 83.5% in non-IgE mediated cases. Extensively hydrolyzed casein formulas were the treatment of choice for 69.9%. Soy formulas were the last option. Almost all respondents were aware of the existence of clinical guidelines on CMPA, being European Society of Pediatric Gastroenterology, Hepatology and Nutrition guidelines the most followed (64.4%). Twenty-three percent considered that their knowledge about allergy was inadequate.

CONCLUSIONS

Although CMPA is a prevalent condition that pediatric gastroenterologists have been treating for decades, we found a huge variability on its management. There is potential for improvement in this field among pediatric gastroenterologist in the future.

摘要

引言

在发达国家,食物过敏是一个日益严重的健康问题。牛奶蛋白是婴儿食物过敏的主要原因。如果没有适当的诊断检查,存在过度诊断和诊断不足以及因此过度治疗和治疗不足的高风险。我们研究的目的是分析西班牙儿科胃肠病学家对牛奶蛋白过敏(CMPA)管理的差异。

方法

起草了一份包含50项的问卷,包括李克特量表(从0到5)中的开放式和封闭式问题,并通过西班牙儿科胃肠病学、肝病学和营养学会(SEGHNP)的电子邮件列表进行分发。

结果

在321份问卷中回收了73份。只有3个项目的一致性超过90%。33%的人认为在任何情况下诊断CMPA都需要口服激发试验。25%的人认为去除牛奶后症状改善足以进行诊断。在非IgE介导的病例中,83.5%的人在家中进行口服激发试验。深度水解酪蛋白配方奶粉是69.9%的人的治疗选择。大豆配方奶粉是最后的选择。几乎所有受访者都知道存在关于CMPA的临床指南,其中遵循欧洲儿科胃肠病学、肝病学和营养学会指南的人最多(64.4%)。23%的人认为他们对过敏的知识不足。

结论

尽管CMPA是儿科胃肠病学家已经治疗了几十年的常见病症,但我们发现其管理存在巨大差异。未来儿科胃肠病学家在这一领域有改进的潜力。

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