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拉丁美洲和西班牙语国家儿科胃肠病学组对牛奶蛋白过敏诊断和治疗的理解:由拉丁美洲儿科学胃肠病学、肝病学和营养学学会食物过敏工作组进行的调查结果。

A Latin American and Spanish pediatric gastroenterology group's understanding of cow's milk protein allergy diagnosis and treatment: Results of a survey by the Food Allergy Working Group of the Sociedad Latinoamericana de Gastroenterología, Hepatología y Nutrición Pediátrica.

机构信息

Hospital Nacional Alejandro Posadas, Buenos Aires, Argentina.

Servicio de Pediatría, Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Madrid, España.

出版信息

Rev Gastroenterol Mex (Engl Ed). 2020 Oct-Dec;85(4):382-389. doi: 10.1016/j.rgmx.2019.08.002. Epub 2019 Oct 14.

Abstract

INTRODUCTION

There are discrepancies in the diagnosis and management of cow's milk protein allergy (CMPA) in Spain and Latin America. The aim of the present study was to find out how Spanish and Latin American pediatric gastroenterologists diagnose and treat CMPA.

MATERIAL AND METHODS

Pediatric gastroenterologists, members of the Sociedad Latinoamericana de Gastroenterología, Hepatología y Nutrición, were invited to fill out a structured survey, the results of which were then compared with the 2012 and 2014 diagnosis and treatment guidelines, respectively.

RESULTS

The survey results showed that 17% of the participants follow the diagnostic recommendations based on the published consensus and guidelines. To diagnose non-IgE-mediated CMPA, 15% of the participants utilize IgE-specific skin prick tests, 22% use IgE-specific blood tests, and 45% employ oral food challenges. To diagnose IgE-mediated CMPA the percentages for the same diagnostic methods were 57, 83 and 22%, respectively. Once diagnosis is confirmed, 98% of the participants provide dietary recommendations. In children that are not breastfed, 89% of the participants prescribe an initial extensively hydrolyzed formula, 9% an amino acid formula, 1% a soy formula, and 1% a hydrolyzed rice formula. In patients with IgE-mediated CMPA, 34% of the participants carry out an oral challenge once treatment is completed, 39% according to symptom severity, and 27% in relation to IgE-specific testing.

CONCLUSION

CMPA management is diverse and there is poor adherence to the clinical practice guidelines.

摘要

简介

在西班牙和拉丁美洲,人们对牛奶蛋白过敏(CMPA)的诊断和管理存在差异。本研究旨在了解西班牙和拉丁美洲的儿科胃肠病学家如何诊断和治疗 CMPA。

材料与方法

邀请拉丁美洲胃肠病学、肝病学和营养学学会的儿科胃肠病学家填写一份结构化调查问卷,然后将结果分别与 2012 年和 2014 年的诊断和治疗指南进行比较。

结果

调查结果显示,17%的参与者遵循基于已发表共识和指南的诊断建议。为了诊断非 IgE 介导的 CMPA,15%的参与者使用 IgE 特异性皮肤点刺试验,22%使用 IgE 特异性血液测试,45%进行口服食物挑战。为了诊断 IgE 介导的 CMPA,同样的诊断方法的百分比分别为 57%、83%和 22%。一旦确诊,98%的参与者提供饮食建议。对于未母乳喂养的儿童,89%的参与者开处方的初始广泛水解配方,9%开氨基酸配方,1%开大豆配方,1%开水解大米配方。对于 IgE 介导的 CMPA,34%的参与者在治疗完成后进行口服挑战,39%根据症状严重程度进行,27%根据 IgE 特异性测试进行。

结论

CMPA 的管理方法多种多样,且临床实践指南的遵循情况较差。

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