Dept. of Epidemiology and Health Statistics, Medical College, Qingdao University, Qingdao, China.
Dept. of Epidemiology and Health Statistics, Medical College, Qingdao University, Qingdao, China.
Exp Gerontol. 2018 Mar;103:88-93. doi: 10.1016/j.exger.2018.01.009. Epub 2018 Jan 9.
Longitudinal studies on sleep duration and grip strength decline are limited. This study aimed to evaluate the associations of baseline sleep duration with follow-up grip strength and grip strength changeover time among a large sample of middle-aged and older Chinese.
Data from China Health and Retirement Longitudinal Study, CHARLS (2011-2015), were analyzed. Hand grip strength was measured by dynamometers twice with 4 years interval. Baseline self-reported nighttime sleep duration was collected by questionnaire. Basic demographics, life habits and health status were considered as potential confounders. Multivariate linear regression models with quadratic function and mixed-effects regression models were fitted.
Inverted U-shaped associations occurred between baseline sleep duration and follow-up grip strength for both males (β = 1.011, p = 0.002; β = -0.061, p = 0.014) and females (β = 0.605, p = 0.005, β = -0.041, p = 0.019). Compared to the sleep duration of 7 h, significant interactions of <5 hours-by-time (γ= - 0.966 with SEE = 0.442, p = .029) in males as well as 5-7 hours-by-time (γ= - 0.717 with SEE = 0.294, p = .015), 7-9 hours-by-time (γ= - 0.632 with SEE = 0.311, p = .042) and >9 hours-by-time (γ= - 1.567 with SEE = 0.560, p = .005) in females were found.
For both males and females, compared to the intermediate sleep duration, shorter or longer sleep may predict the weaker follow-up grip strength and the faster rate of hand grip strength decline over time.
关于睡眠时间和握力下降的纵向研究有限。本研究旨在评估在中国中老年人群中，大量样本的基线睡眠持续时间与随访握力以及随时间推移的握力变化之间的关系。
对中国健康与养老追踪调查（CHARLS，2011-2015 年）的数据进行分析。使用测力计两次测量，两次测量之间间隔 4 年。通过问卷调查收集基线时的夜间睡眠时间。基本人口统计学、生活习惯和健康状况被认为是潜在的混杂因素。使用多元线性回归模型和混合效应回归模型进行拟合。
男性（β=1.011，p=0.002；β=-0.061，p=0.014）和女性（β=0.605，p=0.005；β=-0.041，p=0.019）的基线睡眠时间与随访握力之间呈倒 U 型关系。与 7 小时的睡眠时间相比，男性的<5 小时-时间（γ=-0.966，SE=0.442，p=0.029）以及女性的 5-7 小时-时间（γ=-0.717，SE=0.294，p=0.015）、7-9 小时-时间（γ=-0.632，SE=0.311，p=0.042）和>9 小时-时间（γ=-1.567，SE=0.560，p=0.005）之间存在显著的交互作用。
对于男性和女性来说，与中等睡眠时间相比，较短或较长的睡眠时间可能预示着随访握力较弱，以及随时间推移握力下降的速度较快。
