Guo Jing, Fei Yue, Li Junqin, Zhang Lisan, Luo Qiong, Chen Guangdi
Department of Public Health, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Institute of Obstetrics and Gynecology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
BMJ Open. 2016 Sep 6;6(9):e011770. doi: 10.1136/bmjopen-2016-011770.
The impact of gender and age on the association between sleep duration and hypertension is not well known in Asians. The objective of this study was to analyse gender- and age-specific associations between sleep duration and prevalent hypertension in middle-aged and elderly Chinese.
Secondary analysis of a cohort sample.
This study used data from the national baseline survey of the China Health and Retirement Longitudinal Study (CHARLS, 2011-2012), covering 150 counties/districts and 450 villages/resident committees from 28 provinces in China.
Community-based subjects were drawn from the CHARLS through multistage probability sampling. Overall, this study included 9086 eligible subjects aged 45 years or above.
Self-reported sleep duration was obtained using a structured questionnaire. The mean of three measures of systolic blood pressure and diastolic blood pressure was calculated. By gender and age groups (45-60 years, middle-aged; ≥60 years, elderly), relationships between self-reported sleep duration and prevalent hypertension were examined using logistic regression models to estimate OR and 95% CIs.
Compared with the reference group (≥7 and <8 hours/night), the group who had less sleep (<6 hours/night) had a higher likelihood of hypertension in the whole sample (OR 1.26, 95% CI 1.04 to 1.52). Significant ORs (95% CIs) of hypertension were 1.68 (1.17 to 2.42), 1.69 (1.11 to 2.59) and 2.21 (1.29 to 3.80) for <6, 6-7 (≥6 and <7) and 8-9 (≥8 and <9) hours/night, respectively, in middle-aged men but not women. Interestingly, a significant association was observed between long sleep duration (≥9 hours/night) and hypertension in middle-aged women (OR 1.55, 95% CI 1.02 to 2.35) but not in men.
Extremes of sleep duration increased the likelihood of prevalent hypertension in middle-aged Chinese depending on gender, suggesting that appropriate strategies for improvement in sleep health are required.
在亚洲人群中,性别和年龄对睡眠时间与高血压之间关联的影响尚不清楚。本研究的目的是分析中国中老年人中,睡眠时间与高血压患病率之间的性别和年龄特异性关联。
队列样本的二次分析。
本研究使用了中国健康与养老追踪调查(CHARLS,2011 - 2012年)全国基线调查的数据,该调查覆盖了中国28个省份的150个县/区和450个村庄/居民委员会。
通过多阶段概率抽样从CHARLS中选取社区受试者。总体而言,本研究纳入了9086名年龄在45岁及以上的合格受试者。
使用结构化问卷获取自我报告的睡眠时间。计算收缩压和舒张压三次测量值的平均值。按性别和年龄组(45 - 60岁,中年;≥60岁,老年),使用逻辑回归模型检验自我报告的睡眠时间与高血压患病率之间的关系,以估计比值比(OR)和95%可信区间(CI)。
与参照组(每晚≥7小时且<8小时)相比,睡眠时间较短(每晚<6小时)的组在整个样本中患高血压的可能性更高(OR = 1.26,95%CI为1.04至1.52)。中年男性中,每晚<6小时、6 - 7小时(≥6小时且<7小时)和8 - 9小时(≥8小时且<9小时)患高血压的显著OR(95%CI)分别为1.68(1.17至2.42)、1.69(1.11至2.59)和2.21(1.29至3.80),而女性则无此情况。有趣的是,中年女性中观察到睡眠时间长(每晚≥9小时)与高血压之间存在显著关联(OR = 1.55,95%CI为1.02至2.35),而男性中未观察到这种关联。
睡眠时间过长或过短都会增加中国中年人群患高血压的可能性,且存在性别差异,这表明需要采取适当的策略来改善睡眠健康。