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肝切除术后的非计划性再次手术:危险因素及结局分析

Unplanned reoperation after hepatectomy: an analysis of risk factors and outcomes.

作者信息

Lyu Heather G, Sharma Gaurav, Brovman Ethan Y, Ejiofor Julius, Urman Richard D, Gold Jason S, Whang Edward E

机构信息

Department of Surgery, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA; Center for Perioperative Research, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA.

Department of Surgery, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA; Center for Perioperative Research, Brigham and Women's Hospital/Harvard Medical School, Boston, MA, USA.

出版信息

HPB (Oxford). 2018 Jul;20(7):591-596. doi: 10.1016/j.hpb.2017.12.006. Epub 2018 Jan 11.

Abstract

BACKGROUND/PURPOSE: Reoperation is being increasingly utilized as a metric for surgical care quality. The aim of this study was to identify the incidence of and risk factors for unplanned reoperation following index hepatectomy.

METHODS

Pre, intra- and post-operative information of patients who underwent partial hepatectomy in 435 hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program from 2011 to 2013 were analyzed.

RESULTS

343 (4%) of 9195 patients required reoperation within 30 days of index hepatectomy. The index procedures with the highest incidence of reoperation (%) were trisectionectomy (7%) and right hepatectomy (5%). Patients who underwent reoperation had increased index operative duration (323 ± 174 min versus 243 ± 125 min, p < 0.001), postoperative transfusion (57% versus 23%, p < 0.001), wound complications, cardiorespiratory, renal, thromboembolic, and infectious events. Hemorrhage was the most common indication for reoperation (10%). Male gender, ASA class 4, and right hepatectomy or trisectionectomy were independent predictors of reoperation (OR 1.4 [1.1-1.7], p = 0.007; 2.0 [1.3-3.1], p = 0.003; 1.6 [1.2-2.0], p = 0.001 and 2.5 [1.8-3.4], p < 0.001, respectively). All reoperations occurred during index hospitalization and resulted in longer mean length of stay (19 ± 17 days versus 7 ± 7 days, p < 0.001).

CONCLUSION

Reoperation is associated with several patient characteristics and procedural factors in this national sample. Knowledge of these factors can increase awareness of patients at risk for reoperation.

摘要

背景/目的:再次手术越来越多地被用作衡量外科治疗质量的指标。本研究的目的是确定初次肝切除术后计划外再次手术的发生率及危险因素。

方法

分析了2011年至2013年参与美国外科医师学会国家外科质量改进计划的435家医院中接受部分肝切除术患者的术前、术中和术后信息。

结果

9195例患者中有343例(4%)在初次肝切除术后30天内需要再次手术。再次手术发生率(%)最高的初次手术是三段切除术(7%)和右肝切除术(5%)。接受再次手术的患者初次手术时间延长(323±174分钟对243±125分钟,p<0.001),术后输血(57%对23%,p<0.001),伤口并发症、心肺、肾脏、血栓栓塞和感染事件增多。出血是再次手术最常见的原因(10%)。男性、美国麻醉医师协会(ASA)分级4级以及右肝切除术或三段切除术是再次手术的独立预测因素(比值比分别为1.4[1.1 - 1.7],p = 0.007;2.0[1.3 - 3.1],p = 0.003;1.6[1.2 - 2.0],p = 0.001和2.5[1.8 - 3.4],p<0.001)。所有再次手术均发生在初次住院期间,导致平均住院时间延长(19±17天对7±7天,p<0.001)。

结论

在这个全国性样本中,再次手术与多种患者特征和手术因素相关。了解这些因素可提高对有再次手术风险患者的认识。

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