Health Service Research and Development Center of Innovation, VA Puget Sound Health Care System, Seattle, WA; Department of Medicine, University of Washington, Seattle, WA.
Department of Medicine, Stanford University, Palo Alto, CA.
Am J Kidney Dis. 2018 Jul;72(1):42-49. doi: 10.1053/j.ajkd.2017.11.007. Epub 2018 Jan 10.
Little is known about patterns of end-of-life care for patients with advanced kidney disease not treated with maintenance dialysis.
Case series.
SETTING & PARTICIPANTS: A sample of 14,071 patients with sustained estimated glomerular filtration rates < 15mL/min/1.73m treated in the US Veterans Affairs health care system who died during 2000 to 2011. Before death, 12,756 of these patients had been treated with dialysis, 503 had been discussing and/or preparing for dialysis therapy, and for 812, there had been a decision not to pursue dialysis therapy.
Hospitalization and receipt of an intensive procedure during the final month of life, in-hospital death, and palliative care consultation and hospice enrollment before death.
Compared with decedents treated with dialysis, those for whom a decision not to pursue dialysis therapy had been made were less often hospitalized (57.3% vs 76.8%; OR, 0.40 [95% CI, 0.34-0.46]), less often the recipient of an intensive procedure (3.5% vs 24.6%; OR, 0.15 [95% CI, 0.10-0.22]), more often the recipient of a palliative care consultation (52.6% vs 21.6%; OR, 4.19 [95% CI, 3.58-4.90]), more often used hospice services (38.7% vs 18.2%; OR, 3.32 [95% CI, 2.83-3.89]), and died less frequently in a hospital (41.4% vs 57.3%; OR, 0.78 [95% CI, 0.74-0.82]). Hospitalization (55.5%; OR, 0.39 [95% CI, 0.32-0.46]), receipt of an intensive procedure (13.7%; OR, 0.60 [95% CI, 0.46-0.77]), and in-hospital death (39.0%; OR, 0.47 [95% CI, 0.39-0.56]) were also less common among decedents who had been discussing and/or preparing for dialysis therapy, but their use of palliative care and hospice services was similar.
Findings may not be generalizable to groups not well represented in the Veterans Affairs health care system.
Among decedents, patients not treated with dialysis before death received less intensive patterns of end-of-life care than those treated with dialysis. Decedents for whom there had been a decision not to pursue dialysis therapy before death were more likely to receive palliative care and hospice.
对于未接受维持性透析治疗的晚期肾病患者的临终关怀模式知之甚少。
病例系列。
在美国退伍军人事务部医疗保健系统中接受持续估计肾小球滤过率<15mL/min/1.73m 治疗的 14071 名患者的样本,这些患者在 2000 年至 2011 年期间死亡。在死亡前,这些患者中有 12756 人接受了透析治疗,503 人正在讨论和/或准备透析治疗,812 人决定不进行透析治疗。
在生命的最后一个月,住院和接受强化治疗、院内死亡、临终关怀咨询和死亡前入住临终关怀。
与接受透析治疗的死者相比,决定不进行透析治疗的死者住院治疗的可能性较小(57.3% vs 76.8%;OR,0.40 [95%CI,0.34-0.46]),接受强化治疗的可能性较小(3.5% vs 24.6%;OR,0.15 [95%CI,0.10-0.22]),接受姑息治疗咨询的可能性更大(52.6% vs 21.6%;OR,4.19 [95%CI,3.58-4.90]),接受临终关怀服务的可能性更大(38.7% vs 18.2%;OR,3.32 [95%CI,2.83-3.89]),住院死亡的可能性较小(41.4% vs 57.3%;OR,0.78 [95%CI,0.74-0.82])。住院治疗(55.5%;OR,0.39 [95%CI,0.32-0.46])、接受强化治疗(13.7%;OR,0.60 [95%CI,0.46-0.77])和院内死亡(39.0%;OR,0.47 [95%CI,0.39-0.56])的可能性也较低在正在讨论和/或准备透析治疗的死者中,但他们使用姑息治疗和临终关怀服务的情况相似。
研究结果可能不适用于退伍军人事务部医疗保健系统中代表性不足的人群。
在死者中,未在死亡前接受透析治疗的患者接受的临终关怀模式不及接受透析治疗的患者密集。在死亡前决定不进行透析治疗的死者更有可能接受姑息治疗和临终关怀。