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《老年患者的透析:临床医生实用指南》

Dialysis in the Elderly: A Practical Guide for the Clinician.

作者信息

Satish Aparna, Agrohi Jhalak, Rangaswamy Dharshan, Prabhu Ravindra Attur, Nagaraju Shankar Prasad, Rao Indu Ramachandra, Bhojaraja Mohan V, Shenoy Srinivas Vinayak

机构信息

Department of Anaesthesia, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

Department of Nephrology, Kasturba Medical College Manipal, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

出版信息

Int J Nephrol. 2025 Feb 23;2025:9538115. doi: 10.1155/ijne/9538115. eCollection 2025.

Abstract

The increasing prevalence of elderly patients with end-stage kidney disease (ESKD) poses unique challenges in nephrology. These patients often present with multiple comorbidities, cognitive impairments, and frailty, which significantly impact treatment options and outcomes. Conservative kidney management (CKM) offers a viable alternative to dialysis for many elderly patients by focusing on symptom management and enhancing quality of life rather than merely prolonging life. However, clinicians face difficulties in approaching patients and deciding between CKM and dialysis. In addition, advocating for dialysis involves challenges in selecting the appropriate modality and vascular access. Nutritional management, often overlooked, is critical due to the high prevalence of protein-energy wasting and sarcopenia among elderly dialysis patients. Similar to the initiation of dialysis, there are dilemmas in determining when to withdraw from dialysis. This practical review aims to guide clinicians through the complex and challenging process of managing dialysis in the elderly, emphasizing a holistic, patient-centered approach that prioritizes quality of life. A multidisciplinary strategy, integrating clinical expertise and patient autonomy, is essential to address the complex needs of this vulnerable population.

摘要

老年终末期肾病(ESKD)患者日益增多,给肾脏病学带来了独特挑战。这些患者常伴有多种合并症、认知障碍和身体虚弱,这对治疗方案和治疗结果有显著影响。对于许多老年患者而言,保守肾脏管理(CKM)通过专注于症状管理和提高生活质量而非仅仅延长生命,为透析提供了一种可行的替代方案。然而,临床医生在接触患者以及在CKM和透析之间做出决策时面临困难。此外,在倡导透析时,在选择合适的透析方式和血管通路方面也存在挑战。由于老年透析患者中蛋白质能量消耗和肌肉减少症的高患病率,常常被忽视的营养管理至关重要。与开始透析类似,在决定何时停止透析方面也存在困境。这篇实用综述旨在指导临床医生应对老年患者透析管理这一复杂且具有挑战性的过程,强调采用以患者为中心的整体方法,将生活质量放在首位。整合临床专业知识和患者自主权的多学科策略对于满足这一弱势群体的复杂需求至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b3a/11872294/4ccd78fa59ee/IJN2025-9538115.001.jpg

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