Han Jennifer, Jain Samay
Prog Neurol Surg. 2018;33:25-40. doi: 10.1159/000480719. Epub 2018 Jan 12.
Great progress has been made in expanding our understanding of the natural history of movement disorders, leading to impressive advancements in their medical and surgical management. Movement disorders are a diverse group of diseases, varying widely in clinical characteristics and evolution. Some are monosymptomatic while others have associated motor and nonmotor features. Some are static while others follow a progressive course. This chapter will review common primary and secondary movement disorders: Parkinson disease and other forms of Parkinsonism, essential tremor and its differential diagnoses, dystonia and tic disorders. Herein, we will provide an overview of the clinical presentation and prognosis of the primary and secondary movement disorders most relevant to discussions of surgical candidacy.
在拓展我们对运动障碍自然史的理解方面已取得了巨大进展，这使得运动障碍的药物和手术治疗取得了令人瞩目的进步。运动障碍是一组多样的疾病，其临床特征和演变差异很大。有些是单症状的，而另一些则伴有运动和非运动特征。有些是静止性的，而另一些则呈进行性病程。本章将回顾常见的原发性和继发性运动障碍：帕金森病和其他形式的帕金森综合征、特发性震颤及其鉴别诊断、肌张力障碍和抽动障碍。在此，我们将概述与手术候选资格讨论最相关的原发性和继发性运动障碍的临床表现和预后。
