Benali Sebastien, Johnston Patrick R, Gholipour Ali, Dugan Monet E, Heberlein Keith, Bhat Himanshu, Bixby Sarah D
Department of Radiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA.
Siemens Medical Solutions, Charlestown, MA, USA.
Skeletal Radiol. 2018 Jun;47(6):821-831. doi: 10.1007/s00256-017-2868-2. Epub 2018 Jan 13.
To compare knee MRI performed with the integrated parallel acquisition technique (PAT) and simultaneous multislice (SMS) turbo spin echo (TSE) T2-weighted (T2w) sequences with conventional TSE sequences in pediatric patients.
This was a retrospective IRB-approved study. Seventy-four subjects (26 male, 48 female, mean age 15.3 years, range 8-20) underwent 3-T MRI of the knee with a T2w TSE pulse sequence prototype with four-fold PAT and SMS acceleration as well as the standard PAT-only accelerated sequences. Images were anonymized and two study folders were created: one examination with only T2w PAT2 images (conventional examination) and one examination with only T2w SMS2/PAT2 sequences (SMS examination). Two readers rated examinations for 15 specific imaging findings and 5 quality metrics. Interreader agreement was measured. Signal to noise (SNR) and contrast to noise (CNR) were measured for SMS and conventional T2w sequences.
Consensus review demonstrated diagnostic quality performance of SMS examinations with respect to all 15 structures. Average area under the curve (AROC) was 0.95 and 0.97 for readers 1 and 2, respectively. The conventional sequence was favored over SMS for four out of five quality metrics (p < 0.001). SNR and CNR were higher for the conventional sequences compared to SMS.
SMS accelerated T2w TSE sequences offer a faster alternative for knee imaging in pediatric patients without compromise in diagnostic performance despite diminished SNR. The four-fold acceleration of SMS is beneficial to pediatric patients who often have difficulty staying still for long MRI examinations.
比较集成并行采集技术（PAT）和同时多切片（SMS）涡轮自旋回波（TSE）T2加权（T2w）序列与传统TSE序列在儿科患者膝关节MRI中的应用。
这是一项经机构审查委员会批准的回顾性研究。74名受试者（26名男性，48名女性，平均年龄15.3岁，范围8 - 20岁）接受了膝关节3-T MRI检查，使用了具有四倍PAT和SMS加速的T2w TSE脉冲序列原型以及仅标准PAT加速序列。图像进行了匿名处理，并创建了两个研究文件夹：一个仅包含T2w PAT2图像的检查（传统检查）和一个仅包含T2w SMS2/PAT2序列的检查（SMS检查）。两名阅片者对15项特定影像学表现和5项质量指标进行评分。测量阅片者间的一致性。测量SMS和传统T2w序列的信噪比（SNR）和对比噪声比（CNR）。
共识性审查表明，SMS检查对所有15个结构均具有诊断质量表现。阅片者1和阅片者2的平均曲线下面积（AROC）分别为0.95和0.97。在五项质量指标中的四项上，传统序列优于SMS（p < 0.001）。与SMS相比，传统序列的SNR和CNR更高。
SMS加速T2w TSE序列为儿科患者膝关节成像提供了一种更快的替代方法，尽管SNR有所降低，但诊断性能不受影响。SMS的四倍加速对经常难以在长时间MRI检查中保持静止的儿科患者有益。
