伴有骨骼肌受累的肺鳞状细胞癌：克什米尔一家三级护理医院的8年研究
Squamous Cell Carcinoma Lung with Skeletal Muscle Involvement: A 8-year Study of a Tertiary Care Hospital in Kashmir.
作者信息
Muzamil Javvid, Bashir Shumail, Guru Faisal R, Nabi Firdousa, Bhat Gull Mohammad
机构信息
Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India.
Department of Chest Medicine, Government Medical College, Srinagar, Jammu and Kashmir, India.
出版信息
Indian J Med Paediatr Oncol. 2017 Oct-Dec;38(4):456-460. doi: 10.4103/ijmpo.ijmpo_169_16.
AIMS
Lung cancer is the most common malignancy throughout the world. Nonsmall cell lung cancer (NSCLC) is the most common type, and squamous cell type is most common in India. Mostly, patients present with chest-related symptoms and signs. Isolated skeletal muscle metastasis (ISMM) is rarely seen. The aim was to see muscle metastasis and its prognosis.
MATERIALS AND METHODS
We are presenting our data of 8 years about this common malignancy with relation to muscle metastasis, either alone or with other system metastasis.
RESULTS
Muscle metastasis is seen 1.5% of patients, with male: female of 8:1. Overall median survival was 15 months and progression-free survival was 12 months.
CONCLUSION
One peculiarity seen was ISMM with no pulmonary system and severe paraneoplastic hypercalcemia. Local therapy may be having an impact on overall survival in metachronous muscle involvement.
目的
肺癌是全球最常见的恶性肿瘤。非小细胞肺癌（NSCLC）是最常见的类型，而鳞状细胞型在印度最为常见。大多数患者表现出与胸部相关的症状和体征。孤立性骨骼肌转移（ISMM）很少见。目的是观察肌肉转移情况及其预后。
材料与方法
我们展示了8年来关于这种常见恶性肿瘤与肌肉转移相关的数据，包括单独的肌肉转移或伴有其他系统转移的情况。
结果
1.5%的患者出现肌肉转移，男性与女性比例为8:1。总体中位生存期为15个月，无进展生存期为12个月。
结论
观察到一个特殊情况是ISMM，无肺部系统受累且伴有严重的副肿瘤性高钙血症。局部治疗可能对异时性肌肉受累患者的总生存期有影响。
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