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Cancer statistics, 2015.癌症统计数据,2015 年。
CA Cancer J Clin. 2015 Jan-Feb;65(1):5-29. doi: 10.3322/caac.21254. Epub 2015 Jan 5.
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Bilateral germ-cell testicular cancer - long-term experience.双侧生殖细胞睾丸癌——长期经验
Klin Onkol. 2013;26(6):421-4. doi: 10.14735/amko2013421.
3
Can testis-sparing surgery for small testicular masses be considered a valid alternative to radical orchiectomy? A prospective single-center study.对于小睾丸肿块,可否考虑保留睾丸手术作为根治性睾丸切除术的有效替代方法?一项前瞻性单中心研究。
Clin Genitourin Cancer. 2013 Dec;11(4):522-6. doi: 10.1016/j.clgc.2013.04.033. Epub 2013 Jun 10.
4
Bilateral testicular germ cell tumours: a systematic review.双侧睾丸生殖细胞肿瘤:系统评价。
BJU Int. 2012 Oct;110(8):1102-9. doi: 10.1111/j.1464-410X.2012.11056.x. Epub 2012 Mar 19.
5
Carcinoma in situ testis, the progenitor of testicular germ cell tumours: a clinical review.睾丸原位癌,睾丸生殖细胞肿瘤的起源:临床综述
Ann Oncol. 2005 Jun;16(6):863-8. doi: 10.1093/annonc/mdi175. Epub 2005 Apr 8.
6
Clinical epidemiology of testicular germ cell tumors.睾丸生殖细胞肿瘤的临床流行病学
World J Urol. 2004 Apr;22(1):2-14. doi: 10.1007/s00345-004-0398-8. Epub 2004 Mar 18.
7
Bilateral testicular tumors: a report of nine cases with long-term follow-up.双侧睾丸肿瘤:9例长期随访报告
Int J Urol. 2002 Mar;9(3):173-7. doi: 10.1046/j.1442-2042.2002.00446.x.
8
Bilateral germ cell cancer of the testis: a report of 11 patients with a long-term follow-up.双侧睾丸生殖细胞癌:11例患者的长期随访报告
BJU Int. 2000 May;85(7):864-8. doi: 10.1046/j.1464-410x.2000.00616.x.
9
Intratubular malignant germ cells (carcinoma in situ) accompanying invasive testicular germ cell tumors.伴有浸润性睾丸生殖细胞肿瘤的管内恶性生殖细胞(原位癌)。
J Urol. 1985 Mar;133(3):413-5. doi: 10.1016/s0022-5347(17)49001-x.

睾丸切除术后异时性睾丸癌:一例罕见病例。

Metachronous Testicular Cancer After Orchiectomy: A Rare Case.

作者信息

Arda Ersan, Cakiroglu Basri, Cetin Gizem, Yuksel Ilkan

机构信息

Urology, Trakya University Medical Faculty.

Urology, Hisar Intercontinental Hospital.

出版信息

Cureus. 2017 Nov 9;9(11):e1833. doi: 10.7759/cureus.1833.

DOI:10.7759/cureus.1833
PMID:29333356
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5760111/
Abstract

Testicular cancer represents approximately 1% of all cancers diagnosed in males. The prevalence of bilateral testicular germ cell tumor cases varies from 1% to 5%. Intratubular germ cell neoplasia (ITGCN) is a precursor for almost all testicular germ cell tumors (TGCT) and is one of the highest risks of developing contralateral testicular cancer. The radical orchiectomy is still preferred for the treatment of testicular cancer. However, in some cases like solitary testis, bilateral cancer or if the tumor size is under 30% percent of the testicular extent, organ-sparing surgery can be an option. There are just a few published reports of metachronous contralateral testicular cancer, developed after orchiectomy with the histopathology of the intratubular germ cell neoplasia.

摘要

睾丸癌约占男性确诊癌症总数的1%。双侧睾丸生殖细胞肿瘤病例的患病率在1%至5%之间。管内生殖细胞瘤变(ITGCN)几乎是所有睾丸生殖细胞肿瘤(TGCT)的前身,也是发生对侧睾丸癌的最高风险之一。根治性睾丸切除术仍是治疗睾丸癌的首选方法。然而,在一些情况下,如单睾、双侧癌症或肿瘤大小占睾丸范围不到30%时,保留器官手术也可作为一种选择。关于睾丸切除术后发生异时性对侧睾丸癌且伴有管内生殖细胞瘤变组织病理学特征的报道仅有几例。