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镥[177Lu]标记生长抑素类似物（Lu-177-DOTA-TATE）注射液在放射性核素治疗中的正确使用手册（第 2 版）。

Manual on the proper use of lutetium-177-labeled somatostatin analogue (Lu-177-DOTA-TATE) injectable in radionuclide therapy (2nd ed.).

机构信息

Faculty of Medicine, Kindai University, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan.

Japanese Society of Nuclear Medicine, 2-28-45 Honkomagome, Bunkyo-ku, Tokyo, 113-0021, Japan.

出版信息

Ann Nucl Med. 2018 Apr;32(3):217-235. doi: 10.1007/s12149-018-1230-7. Epub 2018 Jan 15.

DOI:10.1007/s12149-018-1230-7
PMID:29333565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5852188/
Abstract

Here we present the guideline for the treatment of neuroendocrine tumors using Lu-177-DOTA-TATE on the basis of radiation safety aspects in Japan. This guideline was prepared by a study supported by Ministry of Health, Labour, and Welfare, and approved by Japanese Society of Nuclear Medicine. Lu-177-DOTA-TATE treatment in Japan should be carried out according to this guideline. Although this guideline is applied in Japan, the issues for radiation protection shown in this guideline are considered internationally useful as well. Only the original Japanese version is the formal document.

摘要

在此，我们根据日本的辐射安全方面，提出使用 Lu-177-DOTA-TATE 治疗神经内分泌肿瘤的指南。本指南由厚生劳动省资助的一项研究制定，并得到日本核医学会的认可。在日本，Lu-177-DOTA-TATE 的治疗应遵循本指南进行。虽然本指南仅适用于日本，但本指南中列出的辐射防护问题也被认为具有国际意义。只有日文原版才是正式文件。

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本文引用的文献

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J Gastroenterol. 2015 Jan;50(1):58-64. doi: 10.1007/s00535-014-0934-2. Epub 2014 Feb 6.
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The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours.国际原子能机构、欧洲核医学协会和核医学分子影像学会联合发布的神经内分泌肿瘤肽受体放射性核素治疗实践指南。
Eur J Nucl Med Mol Imaging. 2013 May;40(5):800-16. doi: 10.1007/s00259-012-2330-6.
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Individualized dosimetry of kidney and bone marrow in patients undergoing 177Lu-DOTA-octreotate treatment.个体化剂量测定在接受 177Lu-DOTA-奥曲肽治疗的患者的肾和骨髓中的应用。
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Eur J Nucl Med Mol Imaging. 2011 Dec;38(12):2125-35. doi: 10.1007/s00259-011-1902-1. Epub 2011 Sep 3.
5
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