Chow Maggie L, Kim David, Kamath Sonia, Peng David, Luu Minnelly
Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Pediatr Dermatol. 2018 Mar;35(2):e114-e116. doi: 10.1111/pde.13408. Epub 2018 Jan 15.
A 3-month-old girl with Sturge-Weber syndrome presented with a morbilliform rash, eosinophilia, and fulminant liver failure to our tertiary pediatric hospital. She was diagnosed with drug reaction with eosinophilia and systemic symptoms complicated by viremia and evidence of viral hepatitis on liver biopsy. We discuss the role of viral reactivation in drug reaction with eosinophilia and systemic symptoms and the relevance of antiviral therapy in management.
一名患有斯-韦综合征的3个月大女童因出现麻疹样皮疹、嗜酸性粒细胞增多和暴发性肝衰竭被送至我们的三级儿科医院。她被诊断为伴有嗜酸性粒细胞增多和全身症状的药物反应,并伴有病毒血症以及肝活检显示的病毒性肝炎证据。我们讨论了病毒再激活在伴有嗜酸性粒细胞增多和全身症状的药物反应中的作用以及抗病毒治疗在管理中的相关性。