Zhou W, Zhang B, Huang X, You C J, Zhan B M, Yang R Q, Dong Y F, Li J X, Li P, Hong K, Wu Y Q, Wu Q H, Su H, Bao H H, Cheng X S
Department of Cardiovascular Medicine, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2018 Jan 6;52(1):79-84. doi: 10.3760/cma.j.issn.0253-9624.2018.01.015.
To discuss the prevalence and influential factors of stroke among population in Jiangxi Province. Four cities in urban areas and four counties in rural areas were selected firstly, in which two districts or townships were selected; and then three communities or villages were chosen from each district and township, respectively, using the simple random sampling (SRS) method. Finally 15 269 subjects aging 15 years old or above, living in Jiangxi Province ≥6 months were randomly selected to participate in this survey from November 2013 to August 2014. Information of population characteristics, life behavior way, individual disease history were collected through questionnaire survey, and height, weight, waist circumference, blood pressure, body fat rate, visceral fat index and so on were measured by instruments. Risk factors of stroke prevalence were analyzed by the unconditioned logistic regression analysis. A total of 15 269 participants (6 267 males) from 15 364 eligible participants were included in the statistical analysis. Out of which, 7 793 participants came from urban areas, and their average age was (53.04±17.91) years old. In this study, 226 stroke patients (117 males) were found among15 269 participants, including 122 urban participants and 104 rural participants, whose average age was (67.76±9.74) years old. The prevalence of stroke was 1 480.12/100 000 in 2014, which was separately 1 866.92/100 000 and 1 210.84/100 000 among males and females. The prevalence of people aging (45-49) years old was 413.79/100 000 (6/1 450) , while which among people aging 75 years old and above was 3 311.62/100 000 (61/1 842) . The prevalence of stroke among residents in Jiangxi presented an uprising tendency with age increasing (linear-by-linear association χ(2)=62.23, 0.01). The research showed that when other influencing factors including gender, BMI, waist circumference, pulse-pressure difference, VAI, and sleeping time in non-working days were controlled, hypertensive patients had a higher risk of stroke than people without hypertension (6.88, 95 4.90-9.67), drinkers had a higher risk of stroke than non-drinkers (1.56, 95 1.17-2.08), compared with people <65 years old, people aged 65-74 years old and ≥75 years old had a higher risk of stroke, the value of (95) were 1.88 (1.36-2.59) and 1.97 (1.39-2.80), respectively, compared with people with normal body fat percentage, people whose body fat percentage on high side and people who with high body fat percentage had a higher risk of stroke, the value of (95) were 1.71 (1.18-2.48) and 1.74 (1.18-2.56), respectively, people with sleep time >8 h had a higher risk of stroke than those with sleep time of 6-8 h. There was a high stroke prevalence among residents in Jiangxi province. Hypertension, drinking, age, BFP and sleep duration were associated with stroke prevalence. Corresponding measures for high-risk population and risk factors should be strengthened to prevent and control the stroke.
探讨江西省人群脑卒中的患病率及其影响因素。首先选取4个城市市区和4个农村县,每个城市市区和农村县再分别选取2个区或乡;然后从每个区和乡分别选取3个社区或村,采用单纯随机抽样(SRS)方法。最终于2013年11月至2014年8月,从江西省随机选取15 269名年龄在15岁及以上、在江西省居住≥6个月的受试者参与本调查。通过问卷调查收集人口学特征、生活行为方式、个人疾病史等信息,并使用仪器测量身高、体重、腰围、血压、体脂率、内脏脂肪指数等。采用非条件logistic回归分析脑卒中患病率的危险因素。15 364名符合条件的参与者中,共有15 269名参与者(6 267名男性)纳入统计分析。其中,7 793名参与者来自城市地区,平均年龄为(53.04±17.91)岁。本研究中,15 269名参与者中共发现226例脑卒中患者(117名男性),其中城市参与者122例,农村参与者104例,平均年龄为(67.76±9.74)岁。2014年脑卒中患病率为1 480.12/10万,男性和女性患病率分别为1 866.92/10万和1 210.84/10万。年龄在(45 - 49)岁人群的患病率为413.79/10万(6/1 450),而75岁及以上人群的患病率为3 311.62/10万(61/1 842)。江西省居民脑卒中患病率随年龄增长呈上升趋势(线性趋势检验χ² = 62.23,P < 0.01)。研究表明,在控制性别、BMI、腰围、脉压差、内脏脂肪指数和非工作日睡眠时间等其他影响因素后,高血压患者发生脑卒中的风险高于非高血压患者(OR = 6.88,95%CI 4.90 - 9.67),饮酒者发生脑卒中的风险高于不饮酒者(OR = 1.56,95%CI 1.17 - 2.08),与65岁以下人群相比,65 - 74岁和≥75岁人群发生脑卒中的风险更高,OR(95%CI)分别为1.88(1.36 - 2.59)和1.97(1.39 - 2.80),与体脂百分比正常的人群相比,体脂百分比偏高和体脂百分比高的人群发生脑卒中的风险更高,OR(95%CI)分别为1.71(1.18 - 2.48)和1.74(1.18 - 2.56),睡眠时间>8小时的人群发生脑卒中的风险高于睡眠时间为6 - 8小时的人群。江西省居民脑卒中患病率较高。高血压、饮酒、年龄、体脂百分比和睡眠时间与脑卒中患病率相关。应加强针对高危人群和危险因素的相应措施以预防和控制脑卒中。