Rho Seung Sun, Woo Young Sup, Bahk Won-Myong
Department of Psychiatry, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 10, 63-ro, Seoul, 07345, Republic of Korea.
BMC Complement Altern Med. 2018 Jan 15;18(1):14. doi: 10.1186/s12906-018-2081-4.
Impairment of cognitive function as well as negative symptom is the major factor causing the decline of a patient's functioning in chronic stages of schizophrenia. However, until now, there were no definite treatment options that could effectively reduce the impairment.
We report a case of mood dysregulation associated with use of Ginkgo biloba in a patient with schizophrenia. After Ginkgo biloba was given, the patient experienced cluster symptoms of mood dysregulation including irritability, difficulty in controlling anger, agitation and restlessness. We estimated the possibility as "probable" according to Naranjo scale considering circumstantial evidence.
This case suggests that Ginkgo biloba may have caused mood dysregulation in this patient. Although it is generally accepted as safe, more attention should be given to the adverse effect when treating with Ginkgo biloba.
认知功能损害以及阴性症状是导致精神分裂症慢性期患者功能下降的主要因素。然而，迄今为止，尚无明确的治疗方案能够有效减轻这种损害。
我们报告一例精神分裂症患者使用银杏叶后出现情绪失调的病例。服用银杏叶后，患者出现了情绪失调的一系列症状，包括易怒、难以控制愤怒、激动和坐立不安。根据纳朗霍量表并考虑间接证据，我们将可能性评估为“很可能”。
该病例表明银杏叶可能导致了该患者的情绪失调。尽管银杏叶通常被认为是安全的，但在使用银杏叶进行治疗时，应更加关注其不良反应。
