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健康焦虑症状的预测因素及其后果:一项新的双胞胎建模研究。

Predictors and consequences of health anxiety symptoms: a novel twin modeling study.

机构信息

Adult Mental Health Department, Parc Taulí University Hospital, Universitat Autònoma de Barcelona, Sabadell, Spain.

Carlos III Health Institute, CIBERSAM (Centro de Investigación en Red de Salud Mental), Barcelona, Spain.

出版信息

Acta Psychiatr Scand. 2018 Mar;137(3):241-251. doi: 10.1111/acps.12850. Epub 2018 Jan 15.

Abstract

OBJECTIVE

The question of how to best conceptualize health anxiety (HA) from a diagnostic and etiological perspective remains debated. The aim was to examine the relationship between HA and the symptoms of anxiety and obsessive-compulsive-related disorders in a normative twin population.

METHOD

Four hundred and ninety-six monozygotic adult twin pairs from the Australian Twin Registry participated in the study (age, 34.4 ± 7.72 years; 59% females). Validated scales were used to assess each domain. We applied a twin regression methodology-ICE FALCON-to determine whether there was evidence consistent with 'causal' relationships between HA and other symptoms by fitting and comparing model estimates.

RESULTS

Estimates were consistent with higher levels of obsessing ('unwanted thoughts') (P = 0.008), social anxiety (P = 0.03), and body dysmorphic symptoms (P = 0.008) causing higher levels of HA symptoms, and with higher levels of HA symptoms causing higher levels of physical/somatic anxiety symptoms (P = 0.001).

CONCLUSION

Obsessional thoughts, body dysmorphic concerns, and social anxiety symptoms may have a causal influence on HA. To report physical/somatic anxiety appears to be a consequence of the underlying presence of HA-related fears. Should our results be confirmed by longitudinal studies, the evaluation and treatment of HA may benefit from the consideration of these identified risk factors.

摘要

目的

从诊断和病因学的角度来看,如何最好地概念化健康焦虑(HA)仍然存在争议。本研究旨在检查正常双胞胎人群中 HA 与焦虑和强迫相关障碍症状之间的关系。

方法

496 对来自澳大利亚双胞胎登记处的成年同卵双胞胎参与了这项研究(年龄,34.4±7.72 岁;59%为女性)。使用经过验证的量表评估每个领域。我们应用双回归方法-ICE FALCON-通过拟合和比较模型估计来确定 HA 和其他症状之间是否存在“因果”关系的证据。

结果

估计结果与更高水平的强迫观念(“杂念”)(P=0.008)、社交焦虑(P=0.03)和躯体变形症状(P=0.008)导致更高水平的 HA 症状一致,而更高水平的 HA 症状导致更高水平的身体/躯体焦虑症状(P=0.001)。

结论

强迫观念、躯体变形担忧和社交焦虑症状可能对 HA 有因果影响。报告身体/躯体焦虑似乎是 HA 相关恐惧的潜在存在的后果。如果我们的结果得到纵向研究的证实,那么对 HA 的评估和治疗可能受益于考虑这些已确定的风险因素。

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