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种植体周围炎的组织病理学和显微放射学特征。病例报告。

Histopathological and microradiological features of peri-implantitis. A case report.

作者信息

Ayna Mustafa, Gulses Aydin, Ziebart Thomas, Neff Andreas, Açil Yahya

机构信息

Mevki Military Hospital 06130 Diskapi Altindag, Ankara, Turkey.

出版信息

Stomatologija. 2017;19(3):97-100.

Abstract

AIM

The aim of this study was to describe the histological characteristics of a peri-implantitis case in the anterior maxilla.

CASE REPORT

A dental implant inserted in the missing upper right lateral incisor region has been removed with its adjacent tissues. The samples were placed in 4% formalin for 10 days and, were embedded in methacrylate prior to sawing and grinding. The samples were processed with Donath´s sawing and grinding technique, stained with toluidine blue and mounted on high-sensitivity plates for histology and microradiography. The structure of the connective tissue revealed that there was a lack of collagen fibers running parallel to the implant surface. The connective tissue showed a loose granulation tissue with medium-density lymphocyte infiltration and neutrophilic leukocytes. In addition to the collagen loss in the infiltrated tissue, an excessive bone resorption was present. Peripherally, the light microscopy showed the osteoclasts and their adhesive apparatus which promote bone resorption.

CONCLUSION

With the increasing number of implants being placed, peri-implantitis has become much more prevalent. Every additional study focusing on the characteristics of peri-implantitis would be beneficial to gain an understanding of bone and soft tissue behavior around the implant and could help to develop appropriate therapeutic approaches for peri-implant disease.

摘要

目的

本研究旨在描述一例上颌前部种植体周围炎病例的组织学特征。

病例报告

一枚植入右上颌侧切牙缺失区的牙种植体及其相邻组织已被移除。样本置于4%甲醛中10天,然后在锯切和研磨前包埋于甲基丙烯酸酯中。样本采用多纳特锯切和研磨技术处理,用甲苯胺蓝染色,并安装在高灵敏度载玻片上用于组织学和显微放射摄影。结缔组织的结构显示,缺乏与种植体表面平行排列的胶原纤维。结缔组织呈现为疏松的肉芽组织,伴有中等密度的淋巴细胞浸润和中性粒细胞。除了浸润组织中的胶原流失外,还存在过度的骨吸收。在周边,光学显微镜显示破骨细胞及其促进骨吸收的附着装置。

结论

随着种植体植入数量的增加,种植体周围炎变得更加普遍。每一项关注种植体周围炎特征的额外研究都将有助于了解种植体周围的骨和软组织行为,并有助于开发针对种植体周围疾病的适当治疗方法。

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