Department of Periodontology, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
J Clin Periodontol. 2011 Jan;38(1):58-64. doi: 10.1111/j.1600-051X.2010.01631.x. Epub 2010 Nov 24.
To analyse the effect of surgical treatment of peri-implantitis without systemic antibiotics at different types of implants.
Four implants representing four different implant systems - turned (Biomet 3i), TiOblast (Astra Tech AB), SLA (Straumann AG) and TiUnite (Nobel Biocare AB) were placed in the left side of the mandible in six dogs, 3 months after tooth extraction. Experimental peri-implantitis was initiated by placement of ligatures and plaque formation. The ligatures were removed when about 40-50% of the supporting bone was lost. Four weeks later, surgical therapy including mechanical cleaning of implant surfaces was performed. No systemic antibiotics or local chemical antimicrobial therapy were used. After 5 months, block biopsies were obtained and prepared for histological analysis.
Two of the TiUnite implants were lost after surgical therapy. Radiographic bone gain occurred at implants with turned, TiOblast and SLA surfaces, while at TiUnite implants additional bone loss was found after treatment. Resolution of peri-implantitis was achieved in tissues surrounding implants with turned and TiOblast surfaces.
Resolution of peri-implantitis following treatment without systemic or local antimicrobial therapy is possible but the outcome of treatment is influenced by implant surface characteristics.
分析不同类型种植体在不使用全身抗生素的情况下治疗种植体周围炎的效果。
在 6 只狗中，拔牙后 3 个月，在其下颌左侧分别植入 4 个种植体，代表 4 种不同的种植系统——经表面处理的（Biomet 3i）、TiOblast（Astra Tech AB）、SLA（Straumann AG）和 TiUnite（Nobel Biocare AB）。通过放置结扎线和形成菌斑来引发实验性种植体周围炎。当大约 40-50%的支持骨丧失时，去除结扎线。4 周后，进行包括清洁种植体表面的手术治疗。未使用全身抗生素或局部化学抗菌治疗。5 个月后，获得块状活组织检查并进行组织学分析。
在手术治疗后，有两个 TiUnite 种植体丢失。在具有经表面处理的、TiOblast 和 SLA 表面的种植体上发生了放射状骨增益，而在 TiUnite 种植体上，在治疗后发现了额外的骨损失。在具有经表面处理的和 TiOblast 表面的种植体周围组织中，实现了种植体周围炎的缓解。
在不使用全身或局部抗菌治疗的情况下，治疗种植体周围炎是可能的，但治疗结果受到种植体表面特征的影响。
