Dahl R, Harving H, Henriksen J, Rønne K, Schøler P
Allergy. 1985 Oct;40(7):501-5. doi: 10.1111/j.1398-9995.1985.tb00257.x.
Procaterol, a new beta-2 adrenoceptor stimulant, was studied in a double-blind, placebo-controlled, cross-over trial in patients with bronchial asthma. Oral procaterol 50 micrograms b.d., procaterol 100 micrograms b.d., and terbutaline 5 mg t.i.d., were compared when given randomly in 1-week treatment periods. The best clinical effect was found with terbutaline. Both anti-asthmatic and tremorgenic effects of procaterol were dose-related. Procaterol appeared effective in the doses tested, and a twice daily regimen would appear to be suitable with this drug.
丙卡特罗是一种新型β₂肾上腺素能受体激动剂，在一项针对支气管哮喘患者的双盲、安慰剂对照、交叉试验中进行了研究。在为期1周的治疗期内随机给予口服丙卡特罗50微克每日两次、丙卡特罗100微克每日两次以及特布他林5毫克每日三次，并进行比较。发现特布他林的临床效果最佳。丙卡特罗的平喘作用和致震颤作用均与剂量相关。在所测试的剂量下，丙卡特罗似乎有效，且每日两次的给药方案似乎适用于该药物。
