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非诺特罗治疗哮喘

Fenoterol in asthma.

作者信息

Anderson G, Wilkins E, Jariwalla A G

出版信息

Br J Dis Chest. 1979 Jan;73(1):81-4.

PMID:373786
Abstract

Fenoterol is a beta 2-sympathomimetic bronchodilator. In a double-blind cross-over trial in 17 asthmatic patients with reversible airway obstruction inhalation of both fenoterol (0.4 mg) and terbutaline (0.5 mg) produced a statistically significant greater increase in peak expiratory flow rate than did placebo. The magnitude and duration of response to fenoterol exceeded that to terbutaline in the doses used. The patients' subjective assessment also suggested the relief of their symptoms with the active drugs. Side effects were minimal.

摘要

非诺特罗是一种β2-拟交感神经支气管扩张剂。在一项针对17名患有可逆性气道阻塞的哮喘患者的双盲交叉试验中,吸入非诺特罗(0.4毫克)和特布他林(0.5毫克)后,与安慰剂相比,呼气峰值流速在统计学上有显著更大的增加。在所使用的剂量下,非诺特罗的反应幅度和持续时间超过了特布他林。患者的主观评估也表明活性药物缓解了他们的症状。副作用最小。

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