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评估患有心脏病的外科手术患者的PIM-2表现及其结果与RACHS-1的相关性。

Assessment of PIM-2 performance among surgical patients with heart disease and correlation of results with RACHS-1.

作者信息

Rezende Raíssa Queiroz, Ricachinevsky Cláudia Pires, Botta Aline, Angeli Viviane Rampon, Nogueira Aldemir José da Silva

机构信息

Hospital da Criança Santo Antônio, Irmandade Santa Casa de Misericórdia de Porto Alegre - Porto Alegre (RS), Brasil.

出版信息

Rev Bras Ter Intensiva. 2017 Oct-Dec;29(4):453-459. doi: 10.5935/0103-507X.20170069.

DOI:10.5935/0103-507X.20170069
PMID:29340536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5764557/
Abstract

OBJECTIVE

To assess the performance of the Pediatric Index of Mortality (PIM) 2 and the Risk Adjustment for Congenital Heart Surgery (RACHS) in the postoperative period of congenital heart disease patients.

METHODS

Retrospective cross-sectional study. Data were collected from patient records to generate the scores and predictions using recommended techniques, demographic data and outcomes. The Mann-Whitney test, Hosmer-Lemeshow test, standardized mortality rate, area under the receiver operating characteristic (ROC) curve, chi square test, Poisson regression with robust variance and Spearman's test were used for statistical analysis.

RESULTS

A total of 263 patients were evaluated, and 72 died (27.4%). These patients presented significantly higher PIM-2 values than survivors (p < 0.001). In the RACHS-1 classification, mortality was progressively higher according to the complexity of the procedure, with a 3.24-fold increase in the comparison between groups 6 and 2. The area under the ROC curve for PIM-2 was 0.81 (95%CI 0.75 - 0.87), while for RACHS-1, it was 0.70 (95%CI 0.63 - 0.77). The RACHS presented better calibration power in the sample analyzed. A significantly positive correlation was found between the results of both scores (rs = 0.532; p < 0.001).

CONCLUSION

RACHS presented good calibration power, and RACHS-1 and PIM-2 demonstrated good performance with regard to their discriminating capacities between survivors and non-survivors. Moreover, a positive correlation was found between the results of the two risk scores.

摘要

目的

评估儿童死亡指数(PIM)2和先天性心脏病手术风险调整(RACHS)在先天性心脏病患者术后的表现。

方法

回顾性横断面研究。从患者记录中收集数据,使用推荐技术、人口统计学数据和结果来生成评分和预测。采用曼-惠特尼检验、霍斯默-莱梅肖检验、标准化死亡率、受试者工作特征(ROC)曲线下面积、卡方检验、稳健方差的泊松回归和斯皮尔曼检验进行统计分析。

结果

共评估了263例患者,72例死亡(27.4%)。这些患者的PIM-2值显著高于幸存者(p < 0.001)。在RACHS-1分类中,根据手术复杂性,死亡率逐渐升高,6组和2组之间的比较增加了3.24倍。PIM-2的ROC曲线下面积为0.81(95%CI 0.75 - 0.87),而RACHS-1为0.70(95%CI 0.63 - 0.77)。在分析的样本中,RACHS表现出更好的校准能力。两个评分结果之间存在显著正相关(rs = 0.532;p < 0.001)。

结论

RACHS表现出良好的校准能力,RACHS-1和PIM-2在区分幸存者和非幸存者方面表现出良好的性能。此外,两个风险评分结果之间存在正相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/67e4d7b44520/rbti-29-04-0453-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/4c64a694e19c/rbti-29-04-0453-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/6d9376a61b7f/rbti-29-04-0453-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/f099dd432d4f/rbti-29-04-0453-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/67e4d7b44520/rbti-29-04-0453-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/4c64a694e19c/rbti-29-04-0453-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/6d9376a61b7f/rbti-29-04-0453-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/f099dd432d4f/rbti-29-04-0453-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d259/5764557/67e4d7b44520/rbti-29-04-0453-g04.jpg

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