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[阿拉伯狒狒血浆中β-内啡肽样免疫反应性及其变化]

[Beta-endorphin-like immunoreactivity of the blood plasma of hamadryas baboons and its changes].

作者信息

Golanov E V, Fufacheva A A, Parin S B

出版信息

Biull Eksp Biol Med. 1985 Dec;100(12):677-9.

PMID:2934100
Abstract

It was established that plasma level of beta-endorphin-like IR in baboons (Papio hamadryas) was 8 +/- 1 fM/ml, and of beta-lipoprotein-like IR- 9 +/- 1 fM/ml. Ratio between beta-endorphin-like and beta-lipoprotein-like IR was 0.9 +/- 0.1. Under the electrical stimulation of the periventricular-perifornical area of hypothalamus, the level of beta EP-IR reached 26 +/- 9 fM/ml while the level of beta LP-IR fell. On the mamillary hypothalamic area stimulating, no similar changes were observed. A considerable increase in the beta EP-IR level, up to 53 +/- 2 fM/ml, was recorded in hemorrhagic shock. Levels of plasma beta EP-IR in baboons and in men are concluded to be close and the increase of them associated with the stress status of baboons.

摘要

已确定狒狒(阿拉伯狒狒)血浆中β-内啡肽样免疫反应(IR)水平为8±1 fM/ml,β-脂蛋白样IR为9±1 fM/ml。β-内啡肽样与β-脂蛋白样IR的比值为0.9±0.1。在下丘脑室周-穹窿周区域受到电刺激时,β-内啡肽免疫反应(β EP-IR)水平达到26±9 fM/ml,而β-脂蛋白免疫反应(β LP-IR)水平下降。刺激下丘脑乳头体区域时,未观察到类似变化。在失血性休克中,记录到β EP-IR水平显著升高,高达53±2 fM/ml。得出结论,狒狒和人类血浆中β EP-IR水平相近,且其升高与狒狒的应激状态有关。

相似文献

1
[Beta-endorphin-like immunoreactivity of the blood plasma of hamadryas baboons and its changes].[阿拉伯狒狒血浆中β-内啡肽样免疫反应性及其变化]
Biull Eksp Biol Med. 1985 Dec;100(12):677-9.
2
Effects of stress and stress-therapy on plasma beta-endorphin-like immunoreactivity.
Methods Find Exp Clin Pharmacol. 1984 Nov;6(11):671-4.
3
Plasma beta-endorphin immunoreactivity during graded cycle ergometry.分级运动试验期间血浆β-内啡肽免疫反应性
Med Sci Sports Exerc. 1987 Jun;19(3):229-33.
4
[Changes in the activity of plasma beta-endorphin-like-immunoreactivity induced by transcutaneous stimulation of the brain].
Boll Soc Ital Biol Sper. 1983 Nov 30;59(11):1704-10.
5
Stress-induced release of pituitary beta-endorphin may be mediated by activation of the brain stem defence areas.应激诱导的垂体β-内啡肽释放可能由脑干防御区的激活介导。
Int J Tissue React. 1987;9(1):55-9.
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Endotoxic shock elicits greater endorphin secretion than hemorrhage.
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[Influence of experimental hemorrhagic shock on plasma beta-endorphin and beta-lipotropin levels].[实验性失血性休克对血浆β-内啡肽和β-促脂素水平的影响]
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8
Effects of hemorrhagic shock and endotoxin shock on plasma levels of beta-endorphin and beta-lipotropin.失血性休克和内毒素休克对血浆β-内啡肽和β-促脂素水平的影响。
Prog Clin Biol Res. 1983;111:185-96.
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Immunoreactive beta-endorphin concentrations in brain and plasma during pregnancy in rats: possible modulation by progesterone and estradiol.大鼠孕期脑和血浆中免疫反应性β-内啡肽浓度:孕酮和雌二醇的可能调节作用
Neuroendocrinology. 1987 May;45(5):381-8. doi: 10.1159/000124763.