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[阿拉伯狒狒血浆中β-内啡肽样免疫反应性及其变化]

[Beta-endorphin-like immunoreactivity of the blood plasma of hamadryas baboons and its changes].

作者信息

Golanov E V, Fufacheva A A, Parin S B

出版信息

Biull Eksp Biol Med. 1985 Dec;100(12):677-9.

PMID:2934100
Abstract

It was established that plasma level of beta-endorphin-like IR in baboons (Papio hamadryas) was 8 +/- 1 fM/ml, and of beta-lipoprotein-like IR- 9 +/- 1 fM/ml. Ratio between beta-endorphin-like and beta-lipoprotein-like IR was 0.9 +/- 0.1. Under the electrical stimulation of the periventricular-perifornical area of hypothalamus, the level of beta EP-IR reached 26 +/- 9 fM/ml while the level of beta LP-IR fell. On the mamillary hypothalamic area stimulating, no similar changes were observed. A considerable increase in the beta EP-IR level, up to 53 +/- 2 fM/ml, was recorded in hemorrhagic shock. Levels of plasma beta EP-IR in baboons and in men are concluded to be close and the increase of them associated with the stress status of baboons.

摘要

已确定狒狒(阿拉伯狒狒)血浆中β-内啡肽样免疫反应(IR)水平为8±1 fM/ml,β-脂蛋白样IR为9±1 fM/ml。β-内啡肽样与β-脂蛋白样IR的比值为0.9±0.1。在下丘脑室周-穹窿周区域受到电刺激时,β-内啡肽免疫反应(β EP-IR)水平达到26±9 fM/ml,而β-脂蛋白免疫反应(β LP-IR)水平下降。刺激下丘脑乳头体区域时,未观察到类似变化。在失血性休克中,记录到β EP-IR水平显著升高,高达53±2 fM/ml。得出结论,狒狒和人类血浆中β EP-IR水平相近,且其升高与狒狒的应激状态有关。

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