脑血流的临床前动脉自旋标记测量
Preclinical Arterial Spin Labeling Measurement of Cerebral Blood Flow.
作者信息
Muir Eric R
机构信息
Department of Ophthalmology, Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
出版信息
Methods Mol Biol. 2018;1718:59-70. doi: 10.1007/978-1-4939-7531-0_4.
Magnetic resonance imaging has been utilized as a quantitative and noninvasive method to image blood flow. Arterial spin labeling (ASL) is an MRI technique that images blood flow using arterial blood water as an endogenous tracer. Herein we describe the use of ASL to measure cerebral blood flow completely noninvasively in rodents, including methods, analysis, and important considerations when utilizing this technique.
磁共振成像已被用作一种定量且无创的血流成像方法。动脉自旋标记（ASL）是一种磁共振成像技术，它利用动脉血中的水作为内源性示踪剂来成像血流。在此，我们描述了在啮齿动物中完全无创地使用ASL测量脑血流量的方法，包括使用该技术时的方法、分析及重要注意事项。
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