Ranchoff R E, Taylor J S
J Am Acad Dermatol. 1985 Dec;13(6):1015-20. doi: 10.1016/s0190-9622(85)70255-1.
High-performance polymerizable anaerobic sealants originated in 1953 and are used to lock metal parts together chemically. A case of hand contact dermatitis from Loctite RC/601, 242, and 504 is reported in a 60-year-old machine assembler. This diagnosis was documented by positive patch tests of the product and of three of the components: polyethylene glycol dimethacrylate, hydroxypropyl, and hydroxyethyl methacrylate. This is the third report of contact dermatitis caused by these sealants in the United States, is the second in the world on hydroxypropyl methacrylate, and is another example of the wide environmental use of potentially sensitizing acrylic resins.
高性能可聚合厌氧密封剂起源于1953年，用于通过化学方式将金属部件固定在一起。据报道，一名60岁的机器装配工因乐泰RC/601、242和504发生手部接触性皮炎。对该产品及其三种成分：聚乙二醇二甲基丙烯酸酯、羟丙基和甲基丙烯酸羟乙酯进行斑贴试验呈阳性，证实了这一诊断。这是美国关于这些密封剂引起接触性皮炎的第三份报告，是世界上关于甲基丙烯酸羟丙酯的第二份报告，也是潜在致敏性丙烯酸树脂在广泛环境中使用的又一实例。
