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甲基丙烯酸羟乙酯引起的接触性皮炎和胃肠道症状

Contact dermatitis and gastrointestinal symptoms from hydroxyethylmethacrylate.

作者信息

Mathias C G, Caldwell T M, Maibach H I

出版信息

Br J Dermatol. 1979 Apr;100(4):447-9. doi: 10.1111/j.1365-2133.1979.tb01648.x.

Abstract

A laboratory technician developed allergic contact dermatitis to hydroxyethylmethacrylate associated with nausea, diarrhoea and persistent paresthesiae of the fingertips. The gastrointestinal symptoms were reproduced by patch testing. Hydroxyethylmethacrylate was demonstrated to pass through vinyl gloves. Cross reactions occurred to methyl-, ethyl-, propyl- and isopropylmethacrylate but not to butyl- or isobutylmethacrylate.

摘要

一名实验室技术员发生了对甲基丙烯酸羟乙酯的过敏性接触性皮炎,伴有恶心、腹泻和指尖持续性感觉异常。通过斑贴试验再现了胃肠道症状。已证实甲基丙烯酸羟乙酯可穿透乙烯基手套。对甲基丙烯酸甲酯、乙酯、丙酯和异丙酯发生交叉反应,但对甲基丙烯酸丁酯或异丁酯不发生交叉反应。

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