Hwang Kyoung Jin, Kim Jiyoung, Joo Eun Yeon, Hong Seung Bong, Hong Seung-Chyul, Seo Dae Won
Department of Neurology, Kyung Hee University School of Medicine, Seoul, Korea.
Department of Neurology, Busan Medical Center, Busan, Korea.
J Epilepsy Res. 2017 Dec 31;7(2):126-128. doi: 10.14581/jer.17021. eCollection 2017 Dec.
Cerebral calcification is a common incidental finding upon brain imaging and its epileptogenicity is often underestimated. Here, we report a case of intractable epilepsy arising in conjunction with a solitary cerebral calcification. A 42-year-old male with intractable epilepsy was admitted to the epilepsy clinic for invasive epilepsy surgery. Brain magnetic resonance imaging revealed a slight high-intensity signal change in the right amygdala and a small, calcified lesion in the right lateral temporal region. The patient underwent invasive monitoring with subdural electrodes. He had five habitual seizures with automatisms and fast activity. These seizures initiated in the right lateral temporal area just above the solitary calcified lesion. Neuropathology of the calcified lesion showed no specific findings apart from a fibrocalcific nodule. Thus, although solitary cerebral calcifications may be an asymptomatic or coincidental finding in some patients, they may also have a highly epileptogenic focus.
脑钙化是脑部影像学检查中常见的偶然发现，其致痫性常常被低估。在此，我们报告一例伴有孤立性脑钙化的难治性癫痫病例。一名患有难治性癫痫的42岁男性因侵入性癫痫手术入住癫痫门诊。脑部磁共振成像显示右侧杏仁核有轻微的高强度信号改变，右侧颞叶外侧区域有一个小的钙化灶。该患者接受了硬膜下电极的侵入性监测。他有五次伴有自动症和快速活动的习惯性发作。这些发作起始于孤立钙化灶上方的右侧颞叶外侧区域。钙化灶的神经病理学检查除了纤维钙化结节外未发现特异性表现。因此，尽管孤立性脑钙化在某些患者中可能是无症状或偶然的发现，但它们也可能有高度致痫灶。
