选择性动脉内栓塞治疗晚期巩膜外葡萄膜黑色素瘤
Selective Intra-Arterial Embolization for Advanced Extrascleral Uveal Melanoma.
作者信息
Villegas Víctor M, Monagas Mariola, Campbell Joseph, Murray Timothy G, Serrano Luis
机构信息
Department of Ophthalmology, University of Puerto Rico, Río Piedras, Puerto Rico.
Bascom Palmer Eye Institute, University of Miami, FL, USA.
出版信息
Ocul Oncol Pathol. 2017 Dec;4(1):44-47. doi: 10.1159/000477772. Epub 2017 Jul 19.
PURPOSE
To report a treatment approach for advanced extrascleral uveal melanoma.
METHODS
We performed clinical examination including magnetic resonance imaging, computed tomography, angiography, and histopathologic analysis.
CASE
A 49-year-old healthy woman presented with a 7-year history of an enlarging pigmented mass in her right orbit. Malignant melanoma was diagnosed after biopsy with immunohistochemical stains. Treatment included selective intra-arterial embolization.
RESULTS
A significant reduction in tumor burden was seen 3 months after intra-arterial embolization. No complications were associated with the treatment.
CONCLUSION
Selective intra-arterial embolization may allow adequate palliative therapy in select cases of advanced extrascleral uveal melanoma.
目的
报告一种针对晚期巩膜外葡萄膜黑色素瘤的治疗方法。
方法
我们进行了包括磁共振成像、计算机断层扫描、血管造影和组织病理学分析在内的临床检查。
病例
一名49岁健康女性，其右眼眶有一色素性肿块，逐渐增大，已有7年病史。活检及免疫组化染色后诊断为恶性黑色素瘤。治疗包括选择性动脉内栓塞。
结果
动脉内栓塞3个月后，肿瘤负荷显著降低。治疗未出现并发症。
结论
对于部分晚期巩膜外葡萄膜黑色素瘤病例，选择性动脉内栓塞可能是一种有效的姑息治疗方法。
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