INSERM 1052, CNRS 5286, Centre de Recherche en Cancérologie de Lyon, Centre Léon Bérard, Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Department of Translational Research and Innovation, Centre Léon Bérard, Lyon, France.
J Oral Pathol Med. 2018 Apr;47(4):388-395. doi: 10.1111/jop.12683. Epub 2018 Feb 13.
Oral squamous cell carcinoma is a major cause of cancer-associated morbidity and mortality and may develop from oral erythroplakia and leukoplakia (OEL), the most common oral potentially malignant lesions. Our objective was to provide a descriptive overview of the global research activity on OEL over the past decades.
We performed a systematic bibliometric analysis of articles and reviews on OEL up to December 31st 2016 using the SCOPUS database. Contribution of each country was analyzed by density-equalizing mapping (DEMP). The overall scientific productivity was analyzed for each journal and country.
A total of 5098 published items (articles or reviews) were identified. They are expected to double by 2040, with an expected number of 400 items per year. Only 4% of all research on oral oncology is focused on OEL. Together with the increasing number of publications since 1980s, an increasing number of international collaborative studies were observed. Journal of Oral Pathology and Medicine and Oral Oncology are the leading journals in terms of number of published items. The US, India, and the UK were the most prolific countries in terms of publications overtime.
We identified the leading journals as well as the leading authors and countries contributing to the research on OEL. International collaborative studies in the field are to be encouraged to refine strategies of oral cancer prevention.
口腔鳞状细胞癌是癌症相关发病率和死亡率的主要原因，可能由口腔红斑病和白斑病（OEL）发展而来，OEL 是最常见的口腔潜在恶性病变。我们的目的是提供过去几十年中 OEL 全球研究活动的描述性概述。
我们使用 SCOPUS 数据库对截至 2016 年 12 月 31 日的 OEL 相关文章和综述进行了系统的文献计量分析。通过密度均衡映射（DEMP）分析每个国家的贡献。对每个期刊和国家的总体科学生产力进行了分析。
共确定了 5098 篇已发表的项目（文章或综述）。预计到 2040 年将翻一番，每年预计有 400 篇。口腔肿瘤学的所有研究中只有 4% 集中在 OEL 上。自 20 世纪 80 年代以来，发表的文章数量不断增加，国际合作研究的数量也在不断增加。《口腔病理学与医学杂志》和《口腔肿瘤学杂志》是发表文章数量最多的主要期刊。就发表的文章数量而言，美国、印度和英国是最具影响力的国家。
我们确定了主要期刊以及对 OEL 研究做出贡献的主要作者和国家。鼓励开展该领域的国际合作研究，以完善口腔癌预防策略。
