Liu Wei, Shen Xuemin, Shen Zhengyu
Department of Stomatology, Fengcheng Hospital of Fengxian District, Shanghai Ninth People's Hospital Fengcheng Branch Hospital, Shanghai, China.
College of Stomatology, Shanghai Jiao Tong University, National Center for Stomatology, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology, Shanghai, China.
J Dent Sci. 2025 Jan;20(1):672-677. doi: 10.1016/j.jds.2024.08.025. Epub 2024 Sep 8.
BACKGROUND/PURPOSE: Oral leukoplakia (OLK) and oral lichen planus (OLP) represent two common oral potentially malignant disorders. It would be interesting to know scientific output and characteristics of studies on OLK and OLP.
This study aimed to investigate and compare scientometric characteristics of articles on OLK and OLP in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern.
A total of 1,191 and 2,288 papers on OLK and OLP were retrieved in the Scopus database, respectively. The total citation count was 31,859 and the index was 75 for articles on OLK, and the total count was 55,491 and the index was 93 for articles on OLP. For OLK research, oral cancer-related cancer risk, cancer diagnosis, carcinogenesis, prognosis, tumor marker, e.g. protein P53 and Ki-67, risk assessment, e.g. tongue site, tobacco and alcohol consumption were distinctive frequent keywords. For OLP research, drug efficacy, immunosuppressive agents, e.g. corticosteroid, triamcinolone acetonide, tacrolimus, and glucocorticoids, inflammation-related T lymphocyte, lymphocytic infiltration, cytokines, e.g. gamma interferon, tumor necrosis factor, and interleukin 6, complication, e.g. hepatitis C and diabetes mellitus, and scoring system-related visual analog scale, pain, anxiety, quality of life, depression, and questionnaire were distinctive keywords.
This study elucidated the comprehensive identification and recognition of the important and relevant research topics concerned, and encouraged more studies in the field of OLK and OLP to refine management strategies of these diseases.
背景/目的：口腔白斑（OLK）和口腔扁平苔藓（OLP）是两种常见的口腔潜在恶性疾病。了解关于OLK和OLP的研究的科学产出及特点会很有意思。
本研究旨在调查和比较Scopus数据库中关于OLK和OLP的文章的科学计量学特征，重点分析能够反映研究方向和关注主题的关键词。
在Scopus数据库中分别检索到1191篇和2288篇关于OLK和OLP的论文。OLK相关文章的总被引次数为31859次，h指数为75；OLP相关文章的总被引次数为55491次，h指数为93。对于OLK研究，与口腔癌相关的癌症风险、癌症诊断、致癌作用、预后、肿瘤标志物（如蛋白质P53和Ki-67）、风险评估（如舌部部位、烟草和酒精消费）是独特的高频关键词。对于OLP研究，药物疗效、免疫抑制剂（如皮质类固醇、曲安奈德、他克莫司和糖皮质激素）、与炎症相关的T淋巴细胞、淋巴细胞浸润、细胞因子（如γ干扰素、肿瘤坏死因子和白细胞介素6）、并发症（如丙型肝炎和糖尿病）以及与评分系统相关的视觉模拟量表、疼痛、焦虑、生活质量、抑郁和问卷是独特的关键词。
本研究阐明了对相关重要研究主题的全面识别和认识，并鼓励在OLK和OLP领域开展更多研究以完善这些疾病的管理策略。
