亨廷顿舞蹈症与阿尔茨海默病中重度情感障碍发生率的比较。
A comparison of the frequency of major affective disorder in Huntington's disease and Alzheimer's disease.
作者信息
Mindham R H, Steele C, Folstein M F, Lucas J
出版信息
J Neurol Neurosurg Psychiatry. 1985 Nov;48(11):1172-4. doi: 10.1136/jnnp.48.11.1172.
Abstract
Matched groups of patients suffering from Huntington's disease and Alzheimer's disease were compared for psychiatric morbidity prior to the onset of dementia. The Huntington's disease group showed twice the incidence of major affective disorder. This finding suggests a specific relationship between Huntington's disease and major affective disorder rather than the latter being a non-specific prodromal feature of dementia.
摘要
对患有亨廷顿舞蹈症和阿尔茨海默病的配对患者组在痴呆症发作前的精神疾病发病率进行了比较。亨廷顿舞蹈症组的重度情感障碍发病率是另一组的两倍。这一发现表明亨廷顿舞蹈症与重度情感障碍之间存在特定关系，而非后者是痴呆症的非特异性前驱特征。
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本文引用的文献
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Familial Alzheimer Dementia: a prevalent disorder with specific clinical features.
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