组织印片作为斯里兰卡皮肤利什曼病组织病理学的辅助诊断方法。
Tissue Impression Smears as a Supplementary Diagnostic Method for Histopathology in Cutaneous Leishmaniasis in Sri Lanka.
机构信息
Department of Parasitology, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Department of Pathology, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
出版信息
Am J Trop Med Hyg. 2018 Mar;98(3):759-762. doi: 10.4269/ajtmh.17-0748. Epub 2018 Jan 11.
Cutaneous leishmaniasis (CL) is diagnosed mainly by light microscopy of smears made using lesion material. Histopathology is usually done in atypical presentations or when lesion smears are negative. Tissue impression smears (TIS) made from skin biopsy specimens were compared with histopathology for the diagnosis of CL. Out of the 111 patients included, 83 (74.8%) were positive by either methods. The TIS was positive in 70.3% whereas histopathology was positive in 56.8% of patients. Tissue impression smears can be used as a supplementary diagnostic test that gives sensitive and rapid results when tissue biopsies are used as the source of lesion material for diagnosis of CL.
皮肤利什曼病（CL）主要通过使用病变材料制作的涂片进行光学显微镜检查来诊断。当病变涂片为阴性或临床表现不典型时，通常进行组织病理学检查。本研究比较了皮肤活检标本制作的组织印片（TIS）与组织病理学检查在 CL 诊断中的应用。在纳入的 111 例患者中，83 例（74.8%）通过任何一种方法均可确诊。TIS 的阳性率为 70.3%，而组织病理学的阳性率为 56.8%。当组织活检被用作病变材料的来源来诊断 CL 时，组织印片可作为一种补充诊断试验，其结果敏感且快速。
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