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升主动脉全置换及冠状动脉再植术的长期结果。

Long-term results with total replacement of the ascending aorta and reimplantation of the coronary arteries.

作者信息

Cabrol C, Pavie A, Mesnildrey P, Gandjbakhch I, Laughlin L, Bors V, Corcos T

出版信息

J Thorac Cardiovasc Surg. 1986 Jan;91(1):17-25.

PMID:2934586
Abstract

From November, 1976, to June, 1983, 100 patients, 84 male and 16 female patients ranging in age from 13 to 74 years, were operated on for aortic insufficiency associated with an aneurysm of the ascending aorta. Twenty patients were in New York Heart Association Class I, 22 in Class II, 51 in Class III, and seven in Class IV. The surgical treatment in all cases consisted of total replacement of the ascending aorta with a tube graft containing a prosthetic aortic valve and reimplantation of the coronary arteries by an intermediate tube graft according to the technique already reported. In 68 patients an uncomplicated annulo-aortic ectasia existed, and in 32, an aortic dissection; nine of the latter group were operated on during the acute phase. The operative mortality for the entire group was 4% (four deaths). One patient has been lost to follow-up during a period ranging from 18 months to 8 years (average 54 months). The late mortality has been 11/96. Among the 84 survivors, clinical improvement is readily apparent (89% are in Class I or II). Twenty-five patients have been restudied by angiography, which revealed a satisfactory coronary and aortic appearance in all cases with neither stenosis nor aneurysm. The actuarial survival rate is 75% at 8 years. In conclusion, the treatment of aortic insufficiency associated with an aneurysm of the ascending aorta by insertion of a composite graft and reimplantation of the coronary arteries through an intermediate Dacron tube is a reliable method with low mortality and excellent long-term results.

摘要

从1976年11月至1983年6月,100例患者接受了手术治疗,其中男性84例,女性16例,年龄在13至74岁之间,均患有升主动脉瘤合并主动脉瓣关闭不全。纽约心脏协会心功能分级为I级的患者有20例,II级22例,III级51例,IV级7例。所有病例的手术治疗均包括用含人工主动脉瓣的人工血管完全置换升主动脉,并根据已报道的技术通过中间人工血管将冠状动脉重新植入。68例患者存在单纯性瓣环主动脉扩张,32例存在主动脉夹层;后一组中有9例在急性期接受了手术。整个组的手术死亡率为4%(4例死亡)。1例患者在18个月至8年(平均54个月)的随访期间失访。晚期死亡率为11/96。在84名幸存者中,临床改善非常明显(89%的心功能为I级或II级)。25例患者接受了血管造影复查,结果显示所有病例的冠状动脉和主动脉情况均令人满意,既无狭窄也无动脉瘤形成。8年时的精算生存率为75%。总之,通过植入复合人工血管并经中间涤纶人工血管重新植入冠状动脉来治疗升主动脉瘤合并主动脉瓣关闭不全是一种可靠的方法,死亡率低,长期效果良好。

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