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新西兰25至29岁人群的癌症负担:是否需要扩大青少年及青年的年龄范围?

The burden of cancer in 25-29 year olds in New Zealand: a case for a wider adolescent and young adult age range?

作者信息

Ballantine Kirsten R, Utley Victoria, Watson Heidi, Sullivan Michael J, Spearing Ruth

机构信息

Analyst, National Child Cancer Network, Christchurch.

House Officer, Tauranga Hospital, Bay of Plenty District Health Board, Tauranga.

出版信息

N Z Med J. 2018 Jan 19;131(1468):15-24.

Abstract

AIMS

New Zealand currently defines the adolescent and young adult (AYA) group for cancer services as young people 12-24 years of age, while other countries favour a designation of 15-29 years. This study was undertaken to compare cancer incidence and survival among 25-29 year olds to New Zealand's younger AYA population and to assess survival for our 15-29 year population against international benchmarks.

METHODS

Diagnostic and demographic information for cancer registrations between 2000 and 2009 for 25-29 year olds was obtained from the New Zealand Cancer Registry. Incidence rates (IR) and five-year relative survival estimates were calculated according to AYA diagnostic group/sub-group, sex and prioritised ethnicity.

RESULTS

1,541 new primary malignant cancers were diagnosed (IR: 588 per million). Five-year relative survival was 85%, but was significantly lower for Māori and Pacific peoples (both 77%) compared to non-Māori/non-Pacific peoples (88%). In the overall 15-29 year AYA cohort, disease-specific outcomes for bone tumours (46%) and breast cancer (64%) were inferior to international standards.

CONCLUSION

New Zealand 25 to 29 year olds are at twice the risk of developing cancer as those 15-24 years. Given that the survival disparities identified were remarkably consistent with those for younger AYA, consideration should be given widening New Zealand's AYA age range.

摘要

目的

新西兰目前将癌症服务的青少年及青年(AYA)群体定义为12至24岁的年轻人,而其他国家则倾向于将其定义为15至29岁。本研究旨在比较25至29岁人群与新西兰较年轻的AYA人群的癌症发病率和生存率,并对照国际基准评估我国15至29岁人群的生存率。

方法

从新西兰癌症登记处获取2000年至2009年期间25至29岁人群癌症登记的诊断和人口统计信息。根据AYA诊断组/亚组、性别和优先种族计算发病率(IR)和五年相对生存率估计值。

结果

共诊断出1541例新的原发性恶性癌症(IR:每百万588例)。五年相对生存率为85%,但与非毛利/非太平洋人群(88%)相比,毛利人和太平洋岛民的生存率(均为77%)显著较低。在整个15至29岁的AYA队列中,骨肿瘤(46%)和乳腺癌(64%)的疾病特异性结局低于国际标准。

结论

新西兰25至29岁人群患癌风险是15至24岁人群的两倍。鉴于所发现的生存差异与较年轻的AYA人群非常一致,应考虑扩大新西兰的AYA年龄范围。

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