Ballantine Kirsten R, Utley Victoria, Watson Heidi, Sullivan Michael J, Spearing Ruth
Analyst, National Child Cancer Network, Christchurch.
House Officer, Tauranga Hospital, Bay of Plenty District Health Board, Tauranga.
N Z Med J. 2018 Jan 19;131(1468):15-24.
New Zealand currently defines the adolescent and young adult (AYA) group for cancer services as young people 12-24 years of age, while other countries favour a designation of 15-29 years. This study was undertaken to compare cancer incidence and survival among 25-29 year olds to New Zealand's younger AYA population and to assess survival for our 15-29 year population against international benchmarks.
Diagnostic and demographic information for cancer registrations between 2000 and 2009 for 25-29 year olds was obtained from the New Zealand Cancer Registry. Incidence rates (IR) and five-year relative survival estimates were calculated according to AYA diagnostic group/sub-group, sex and prioritised ethnicity.
1,541 new primary malignant cancers were diagnosed (IR: 588 per million). Five-year relative survival was 85%, but was significantly lower for Māori and Pacific peoples (both 77%) compared to non-Māori/non-Pacific peoples (88%). In the overall 15-29 year AYA cohort, disease-specific outcomes for bone tumours (46%) and breast cancer (64%) were inferior to international standards.
New Zealand 25 to 29 year olds are at twice the risk of developing cancer as those 15-24 years. Given that the survival disparities identified were remarkably consistent with those for younger AYA, consideration should be given widening New Zealand's AYA age range.
新西兰目前将癌症服务的青少年及青年(AYA)群体定义为12至24岁的年轻人,而其他国家则倾向于将其定义为15至29岁。本研究旨在比较25至29岁人群与新西兰较年轻的AYA人群的癌症发病率和生存率,并对照国际基准评估我国15至29岁人群的生存率。
从新西兰癌症登记处获取2000年至2009年期间25至29岁人群癌症登记的诊断和人口统计信息。根据AYA诊断组/亚组、性别和优先种族计算发病率(IR)和五年相对生存率估计值。
共诊断出1541例新的原发性恶性癌症(IR:每百万588例)。五年相对生存率为85%,但与非毛利/非太平洋人群(88%)相比,毛利人和太平洋岛民的生存率(均为77%)显著较低。在整个15至29岁的AYA队列中,骨肿瘤(46%)和乳腺癌(64%)的疾病特异性结局低于国际标准。
新西兰25至29岁人群患癌风险是15至24岁人群的两倍。鉴于所发现的生存差异与较年轻的AYA人群非常一致,应考虑扩大新西兰的AYA年龄范围。