[Lipid peroxidation as an indicator of the adaptive capacity of patients with chronic bronchitis during sanatorium and health resort treatment with a change in climate and geography].

Lipid peroxidation (LPO) in the blood plasma and erythrocytes was studied in 99 inhabitants of the southern part of West Siberia suffering from chronic bronchitis, of them 64 with obstructive bronchitis. They were sent for treatment to the contrast climatic zone (Yalta, the Crimea), and LPO was examined before the trip and after return in the course of a month (three times). LPO activity at a later stage as compared to the initial one was raised in the patients with signs of disadaptation (54 patients). The time course of LPO up to the initial level was over up to the 12th day after return in the patients with moderate symptoms of disadaptation in the warm season and up to the 30th day in the cold period. LPO activity in the patients with pronounced symptoms of disadaptation was more noticeable, the time course of the indicators up to the initial level was more delayed, particularly in erythrocytes and in the cold season. Thus LPO activity in chronic bronchitis in terms of its expression and period depends on patients' adaptogenicity to contrast change of climatic geographic zones after therapy in a sanatorium.