Bailey C Eric, Jung Francesca, Addicks Benjamin, Esan Olukemi A, Kellermeyer Brian
Department of Otolaryngology, West Virginia University Health Science Center, Morgantown, WV, USA.
School of Medicine, West Virginia University, Morgantown, WV, USA.
Case Rep Otolaryngol. 2017;2017:5982168. doi: 10.1155/2017/5982168. Epub 2017 Nov 14.
Nodular lymphocyte-predominant Hodgkin lymphoma is an uncommon variant of Hodgkin lymphoma. Progressive transformation of germinal centers has been associated with and can develop prior to, concurrent with, or after the diagnosis of nodular lymphocyte-predominant Hodgkin lymphoma. We present a patient with a history of progressive transformation of germinal centers of the right parotid who presented 4 years later with ipsilateral parotid mass and cervical adenopathy. Knowledge of her previous diagnosis raised our concern for lymphoma, influenced our surgical management, and spared the patient additional surgery with risk of facial nerve injury inherent in revision parotidectomy.
结节性淋巴细胞为主型霍奇金淋巴瘤是霍奇金淋巴瘤的一种罕见变体。生发中心进行性转化与结节性淋巴细胞为主型霍奇金淋巴瘤相关，可在其诊断之前、同时或之后发生。我们报告一例有右侧腮腺生发中心进行性转化病史的患者，该患者4年后出现同侧腮腺肿块和颈部淋巴结病。了解她之前的诊断引起了我们对淋巴瘤的关注，影响了我们的手术处理方式，并使患者免于接受存在面神经损伤风险的再次腮腺切除术这一额外手术。
