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由(SBSEC)菌血症引发的严重糖尿病酮症酸中毒的罕见病因:病例报告及文献综述

Unusual cause of severe diabetic ketoacidosis precipitated by (SBSEC) bacteremia: Case report and review of literature.

作者信息

Idrees Sana, Gupta Sonali, Mantilla Miguel, Goyal Pradeep, Hulinsky Ilja

机构信息

Department of Internal Medicine, St. Vincent's Medical Center, Bridgeport, CT, USA.

Department of Radiology, St. Vincent's Medical Center, Bridgeport, CT, USA.

出版信息

IDCases. 2018 Jan 9;11:53-55. doi: 10.1016/j.idcr.2017.12.004. eCollection 2018.

Abstract

Diabetic ketoacidosis is a feared complication in patients with diabetes mellitus and poses high risk of mortality and morbidity unless treated in timely manner. Infection is one of the most common precipitating factors for the development of diabetic ketoacidosis. Bacteremia with Group A and Group B beta hemolytic streptococcal strains are well known, however nonenterococcal Group D strains such as the / (SBSEC) still remains an understudied entity. Here we present a case of a 35-year-old Type I diabetic female presenting with severe diabetic ketoacidosis with overlapping features of hyperosmolar hyperglycemia, precipitated by bacteremia, successfully treated with four-week course of parenteral ceftriaxone. This case report emphasizes the potential importance of SBSEC as an emerging pathologic strain and culprit for triggering diabetic ketoacidosis which requires prompt diagnosis and targeted therapy.

摘要

糖尿病酮症酸中毒是糖尿病患者令人担忧的并发症,若不及时治疗,会带来高死亡率和高发病率风险。感染是糖尿病酮症酸中毒发生的最常见诱发因素之一。A组和B组β溶血性链球菌菌株引起的菌血症是众所周知的,然而非肠球菌D组菌株,如屎肠球菌(SBSEC)仍是一个研究不足的实体。在此,我们报告一例35岁的I型糖尿病女性病例,该患者因菌血症引发严重糖尿病酮症酸中毒,并伴有高渗性高血糖的重叠特征,经四周疗程的肠外头孢曲松治疗成功。本病例报告强调了屎肠球菌作为一种新兴致病菌株以及引发糖尿病酮症酸中毒罪魁祸首的潜在重要性,这需要及时诊断和针对性治疗。

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