Inzunza Gabriel, Rada Gabriel, Majerson Alejandro
Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Proyecto Epistemonikos, Santiago, Chile.
Proyecto Epistemonikos, Santiago, Chile; Departamento de Medicina Interna, Facultad de Medicina, Pontificia Universidad Católica de Chile; Centro Evidencia UC, Pontificia Universidad Católica de Chile, Santiago, Chile; GRADE working group; The Cochrane Collaboration.
Medwave. 2018 Jan 17;18(1):e7134. doi: 10.5867/medwave.2018.01.7134.
Transurethral resection is currently considered as standard endoscopic treatment for lower urinary tract obstruction due to benign hyperplasia under 80 cc. Monopolar resection loops has been traditionally used but bipolar energy has recently displaced precedent technology. The purpose of this summary is to evaluate the efficacy and safety of both technologies.
To answer this question we used Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach.
We identified 13 systematic reviews including 32 primary studies, among them 31 randomized trials. We concluded although there may be no difference in terms of efficacy among both techniques, the use of bipolar energy reduces the incidence of transurethral resection syndrome and probably reduces the risk of bleeding that requires red blood cell transfusion.
经尿道切除术目前被认为是治疗80立方厘米以下良性增生所致下尿路梗阻的标准内镜治疗方法。传统上使用单极切除环,但双极能量最近已取代了先前的技术。本综述的目的是评估这两种技术的疗效和安全性。
为回答这个问题,我们使用了Epistemonikos,这是最大的健康系统评价数据库,通过筛选多个信息来源来维护,包括MEDLINE、EMBASE、Cochrane等。我们从系统评价中提取数据,重新分析原始研究的数据,进行荟萃分析,并使用GRADE方法生成结果总结表。
我们确定了13篇系统评价,包括32项原始研究,其中31项随机试验。我们得出结论,虽然两种技术在疗效方面可能没有差异,但使用双极能量可降低经尿道切除综合征的发生率,并可能降低需要输注红细胞的出血风险。