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哥伦比亚引入肺炎球菌结合疫苗后肺炎球菌性脑膜炎趋势:一项中断时间序列分析。

Pneumococcal meningitis trends after pneumococcal conjugate vaccine introduction in Colombia: An interrupted time-series analysis.

机构信息

a GSK , Bogotá , Colombia.

b GSK , Panamá City , Panamá.

出版信息

Hum Vaccin Immunother. 2018 May 4;14(5):1230-1233. doi: 10.1080/21645515.2018.1425115. Epub 2018 Feb 12.

DOI:10.1080/21645515.2018.1425115
PMID:29351491
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5989909/
Abstract

Colombia introduced mass pneumococcal conjugate vaccination at the end of 2011. Using 2005-2015 surveillance data, we conducted a retrospective interrupted time-series analysis. A significant trend towards reduced monthly was observed in the post-vaccination period (2012-2015) compared with the expected rate, reaching in 2015 a reduction of 90.5% of pneumococcal meningitis. This trend was not observed for control diseases.

摘要

哥伦比亚于 2011 年底推出了大规模肺炎球菌结合疫苗接种。利用 2005-2015 年的监测数据,我们进行了回顾性中断时间序列分析。与预期相比,在接种疫苗后(2012-2015 年),每月发病率呈显著下降趋势,到 2015 年,肺炎球菌性脑膜炎发病率下降了 90.5%。这一趋势在对照疾病中并未观察到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73d/5989909/fddb72412161/khvi-14-05-1425115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73d/5989909/fddb72412161/khvi-14-05-1425115-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c73d/5989909/fddb72412161/khvi-14-05-1425115-g001.jpg

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Pediatr Infect Dis J. 2017 Oct;36(10):1000-1001. doi: 10.1097/INF.0000000000001671.
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PLoS One. 2016 Dec 12;11(12):e0166736. doi: 10.1371/journal.pone.0166736. eCollection 2016.
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Invasive pneumococcal disease burden in hospitalized adults in Bogota, Colombia.
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BMC Infect Dis. 2021 Oct 12;21(1):1059. doi: 10.1186/s12879-021-06769-2.
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Trends in all-cause pneumonia and otitis media in children aged <2 years following pneumococcal conjugate vaccine introduction in Colombia.在哥伦比亚引入肺炎球菌结合疫苗后,2岁以下儿童全因性肺炎和中耳炎的发病趋势。
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