The Radiation Oncology Department of Shandong Cancer Hospital, Affiliated To Shandong University, Jiyan Road 440#, Jinan Shandong, 250117, China.
Biomedical And Multimedia Information Technology (BMIT) Research Group, School Of Information Technologies (SIT), The University Of Sydney, Sydney, Nsw, 2008, Australia.
Sci Rep. 2018 Jan 19;8(1):1254. doi: 10.1038/s41598-018-19576-8.
In this study, we designed an oxygen supply and oxygen saturation monitoring (OSOSM) system. This OSOSM system can provide a continuous supply of oxygen and monitor the peripheral capillary oxygen saturation (SpO2) of patients who accept radiotherapy and use an active breathing coordinator (ABC). A clinical test with 27 volunteers was conducted. The volunteers were divided into two groups based on the tendency of SpO2 decline in breath-holding without the OSOSM system: group A (12 cases) showed a decline in SpO2 of less than 2%, whereas the decline in SpO2 in group B (15 cases) was greater than 2% and reached up to 6% in some cases. The SpO2 of most volunteers declined during rest. The breath-holding time of group A without the OSOSM system was significantly longer than that of group B (p < 0.05) and was extended with the OSOSM system by 26.6% and 27.85% in groups A and B, respectively. The SpO2 recovery time was reduced by 36.1%, and the total rest time was reduced by 27.6% for all volunteers using the OSOSM system. In summary, SpO2 declines during breath-holding and rest time cannot be ignored while applying an ABC. This OSOSM system offers a simple and effective way to monitor SpO2 variation and overcome SpO2 decline, thereby lengthening breath-holding time and shortening rest time.
在这项研究中，我们设计了一种供氧和血氧饱和度监测（OSOSM）系统。该 OSOSM 系统可以为接受放疗并使用主动呼吸控制器（ABC）的患者提供持续的氧气供应，并监测其外周毛细血管血氧饱和度（SpO2）。对 27 名志愿者进行了临床测试。根据志愿者在没有 OSOSM 系统的情况下屏气时 SpO2 下降的趋势，将他们分为两组：A 组（12 例）的 SpO2 下降幅度小于 2%，而 B 组（15 例）的 SpO2 下降幅度大于 2%，在某些情况下甚至达到 6%。大多数志愿者在休息时 SpO2 下降。在没有 OSOSM 系统的情况下，A 组的屏气时间明显长于 B 组（p<0.05），分别延长了 26.6%和 27.85%。SpO2 恢复时间缩短了 36.1%，所有志愿者使用 OSOSM 系统后，总休息时间缩短了 27.6%。综上所述，在应用 ABC 时，不能忽视屏气和休息时 SpO2 的下降。该 OSOSM 系统提供了一种简单有效的监测 SpO2 变化和克服 SpO2 下降的方法，从而延长了屏气时间，缩短了休息时间。
